Synedrela nodiflora (Kochon-gra) : vertus médicinales en extraction alcoolique

Synedrela nodiflora (Kochon-gra, Man-Bôgn, Zèb-dépo, Cochon gras, madame borgne, herbe-à-dépôt, Fat pig, one-eyed lady, deposit grass) — famille Asteracées.

Synonymes scientifiques : Verbesina nodiflorum-L, Ucacou nodiflorum-(L)-Hitch.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 8 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 30 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Normalisatrice des paramètres sériques : MDA, ALT, AST, Bilirubine, SGOT, SGPT

   Partie usitée : Tige.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Kabir T (2014)

     Extrait Since result of biochemical studies of blood sample of carbon tetrachloride treated rats showed significant increase in the level of serum enzyme activities, reflecting the liver injury caused by CCL4 & blood sample from the animals treated with the ethanol extract of SN showed significant decrease in the level of serum marker, indicating the protection of hepatic cells, the extract of above plant could afford significant dose dependent protection against CCL4 induced hepatocellular injury,. It was found that the ethanol extract of SN at a dose of 250mg/kg body weight exhibited significant protective effect by lowering the serum level of alanine aminotransferase (ALT) or serum Glutamate Pyruvate Transferase (SGPT), & 100mg/kg body weight exhibited significant protective effect by lowering both the serum levels of alanine aminotransferase (ALT) or serum Glutamate Pyruvate Transferase (SGPT), aspartate aminotransferase (AST) or serum glutamate oxaloacetate transaminase (SGOT).

   • Selon TASMIIATUL KABIR (2014)

     Extrait Since result of biochemical studies of blood sample of carbon tetrachloride treated rats showed significant increase in the level of serum enzyme activities , reflecting the liver injury caused by CCL4 & blood sample from the animals treated with the ethanol extract of S nodiflora showed significant decrease in the level of serum marker , indicating the protection of hepatic cells , the extract of above plant could afford significant dose dependent protection against CCL4 induced hepatocellular injury. It was found that the ethanol extract of S nodiflora at a dose of 250mg/kg body weight exhibited significant protective effect by lowering the serum level of alanine aminotransferase(ALT) or serum Glutamate Pyruvate Transferase (SGPT), & 100mg/kg body weight exhibited significant protective effect by lowering both the serum levels of alanine aminotransferase (ALT) or serum Glutamate Pyruvate Transferase (SGPT),aspartate aminotransferase (AST) or serum glutamate oxaloacetate transaminase (SGOT).

   • Selon Chaniad P (2021)

     Extrait Moreover, no significant alterations in the biochemical parameters of liver & kidney function & no histological changes in the liver or kidney tissues were observed. Biochemical parameters of liver & kidney function & the histopathology of liver & kidney tissues of the acute toxicity group were then examined.

   • Selon Iqbal M (2016)

     Extrait Serum alanine aminotransferase (ALT), serum aspartate aminotransferase (AST), hepatic antioxidant enzymes, & malondialdehyde (MDA) levels were estimated. Biochemical, immunohistochemical, histological, & ultrastructural findings were in agreement to support the hepatoprotective effect of SN against CCl4-mediated oxidative hepatic damage.

   • Selon Amoateng P (2016)

     Extrait METHODS: The toxicological evaluation of the extract (100, 300 and 1000 mgkg-1) was focused on haematological, serum biochemical parameters and histopathological changes of some isolated organs. CONCLUSIONS: The findings suggest hydroethanolic extract of Synedrella nodiflora (L) Gaertn generally has a low toxicity profile following a 90-day continuous oral administration in male Sprague-Dawley rats under the present Laboratory conditions.

2. 2

   Arthrite, arthrose rhumatoïde rhumatisme, œdème

   Partie usitée : Plante entière.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Forestieri AM (1996)

     Extrait (leaves), Lippia nodiflora (L.) Michx (leaves) & Synedrella nodiflora (Whole plant), were evaluated in pharmacological tests using rats & mice. Antiinflammatory, analgesic & antipyretic activities and toxicity of different extracts (decoction, petroleum ether, ethanol & aqueous extracts) of T: Afrormosiu Laxiflorus (Benth.

   • Selon Haque A (2012)

     Extrait Haque A et al, Antiinflammatory & Insecticidal activities of Synedrella nodiflora, Molecular & Clin Pharm, 2012, 2(2), 60-7- Abstract Methanolic extract of the leaves of Synedrella nodiflora (Asteraceae) has been evaluated for its insecticidal & anti-inflammatory potential against the insect Sitophilus oryzae using surface film method & carrageenan & formalin induced paw edema in rat, respectively. The result suggest into the plant extract could be used as a potential insecticidal as well as potential anti-inflammatory agent.

   • Selon Amoateng P (2011)

     Extrait Conclusions: These findings suggest that hydroethanolic extract of Synedrella nodiflora contains antioxidant principles which may contribute to its traditional use in epilepsy management. The present study aimed at investigating the possible mechanisms of antioxidant effects of the hydroethanolic extract of the whole plant.

   • Selon Oloyede G (2016)

     Extrait Node weed Synedrella nodiflora used traditionally in Nigeria for treating various diseases such as arthritis, rheumatism, dropsy, swellings, oedema, gout and leprosy is one of such plant. The antioxidant properties of plants have been linked to their therapeutic & protective effects against diseases such as inflammation, arthritis, rheumatism, Parkins-on's disease, Alzheimer's disease, cancer, cardiovascular disorders, bacterial & viral infections.

   • Selon LE TTK (2020)

     Extrait nodiflora) has long been used for the treatment of inflammatory diseases, including liver disease, asthma, rheumatism & earache, in tropical countries throughout America, Asia & Africa. In the present study, the anti-inflammatory mechanism of a methanol extract of S.

3. 3

   Douleur, hyperalgie allodynique :(Allodynie : douleur déclenchée par un stimulus normalement indolore.)

   Partie usitée : Plante entière.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Amoateng P (2015)

     Extrait The hydro-ethanolic extract of Synedrella nodiflora (L.) Gaertn whole plant has demonstrated analgesic effects in acute pain models. The present study illustrates an evaluation of the hydro-ethanolic extract of the plant for possible analgesic properties in hyperalgesia and allodynia associated with vincristine-induced neuropathy in rats.

   • Selon Amoateng P (2017)

     Extrait CONCLUSION: The hydroethanolic extract of the whole plant of Synedrella nodiflora possess analgesic effect in paclitaxel-induced. The hydroethanolic extract of the whole plant has demonstrated antinociceptive effect in various animal models of pain.

   • Selon Woode E (2009)

     Extrait J of Pharm &Toxicol, 4: 17-29, 2009-This study presents the effect of an ethanolic extract of the whole plant of Synedrella nodiflora, a plant used in Ghana for the treatment of epilepsy & pain, in formalin-induced pain & acetic acid-induced writhing assay and the possible mode(s) of action of its analgesic action. Woode E et al, Antinociceptive Effects of an Ethanolic Extract of the Whole Plant of Synedrella nodiflora (L.) Gaertn in Mice: Involvement of Adenosinergic Mechanisms.

   • Selon Forestieri AM (1996)

     Extrait (leaves), Lippia nodiflora (L.) Michx (leaves) & Synedrella nodiflora (Whole plant), were evaluated in pharmacological tests using rats & mice. Antiinflammatory, analgesic & antipyretic activities and toxicity of different extracts (decoction, petroleum ether, ethanol & aqueous extracts) of T: Afrormosiu Laxiflorus (Benth.

   • Selon Nahar L (2012)

     Extrait nodiflora (SN) was determined using Folin Ciocalteu reagent, phosphomolybdenum method, free radical scavenging activity by 1,1-diphenyl-2-picryl-hydrazyl (DPPH) & the reducing power activity. Analgesic activity was done by acetic acid & formalin model & CNS depressant activity was measured by the hole cross & open field method.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.