Synsepalum dulcificum (Fruit-miracle) : vertus médicinales en extraction alcoolique

Synsepalum dulcificum (Fruit-miracle, Miracle fruit) — famille Sapotacées.

Synonymes scientifiques : Richadella dulcifica-.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 10 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 53 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Dioso MK (2016)

     Extrait Twenty-five albino rats were induced with type 2 diabetes mellitus using alloxan and were grouped and treated into five treatments (positive control using metformin, 50% fruit extract, 50% leaf extract, 100% fruit extract, 100% leaf extract).Blood glucose level were analyzed and compared. The Hypoglycemic effects of its fruit & leaf extracts on the blood glucose level of alloxan-induced diabetic albino rats were determined & compared with the positive control using Metformin.

   • Selon Olabisi OT (2019)

     Extrait the present study aimed to provide insight into the antidiabetic mechanisms of methanol & flavonoid-rich leaf extracts of Synsepalum dulcificum (MSD and FSD, respectively). Conclusion: Results from this study indicate that increased insulin synthesis, reduction of inflammation & inhibition of carbohydrate metabolizing enzymes are likely mechanisms by which MSD &FSD exert antidiabetic action in type II diabetic rats.

   • Selon -Chen CC (2006)

     Extrait In an attempt to probe a new target to improve insulin resistance, miracle fruit (Synsepalum dulcificum) was employed to investigate the effect on insulin resistance induced by fructose-rich chow in rats. In conclusion, the results suggest that miracle fruit may be used as an adjuvant for treating diabetic patients with insulin resistance because this fruit has the ability to improve insulin sensitivity.

   • Selon Swamy KB (2013)

     Extrait Synsepalum dulcificum or the "miracle fruit" is well known for its taste-Modifying ability. The miracle fruit can be a healthy additive due to its unique characteristics, including sour taste sensation modification as well as its antioxidant & antidiabetic effects.

   • Selon Haddad SG (2020)

     Extrait Haddad SG et al, Antihyperglycemia & hepatoprotective properties of miracle fruit (Synsepalum dulcificum) compared to aspartame in alloxant induced diabetic mice J of Integrative Med, 8(6):514-21, 2020-DOI: https://doi.org/j.joim.2020.09.001,.

2. 2

   Cancer : traitement adjuvant du carcinome colorectal

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Swamy KB (2013)

     Extrait Synsepalum dulcificum or the "miracle fruit" is well known for its taste-Modifying ability. This effect was shown to be related to a glycoprotein called "miraculin." Other beneficial characteristics of this fruit were its antioxidant & anticancer abilities that are due to the various amides existing in the miracle fruit.

   • Selon LU S (2014)

     Extrait The aim of this study was to determine the chemical composition of Synsepalum dulcificum leaf essential oil obtained by steam distillation. In addition, the antitumoral activity using MTT assay of the leaf essential oil exhibited this oil was effective against human K562 cancer cell line in a dose dependent manner.

   • Selon Auteur (2013)

     Extrait The Synsepalum dulcificum leaf total flavonoid was determined & the Technology & conditions was to be optimum by using the response surface method on the basis of single factor experiment. The Synsepalum dulcificum leaf can improve heart Burn, indigestion, poor appetite and other symptoms, such as atherosclerosis, high blood pressure & diabetes.

   • Selon Seong J (2018)

     Extrait dulcificum) Daniell (Sapotaceae) on human colon cancer (HCT-116 & HT-29), human monocytic leukemia (THP-1) & normal (HDFn) cell lines, & its effect on the expression of early apoptotic genes, c-fos & c-jun. dulcificum on HCT-116 & HT-29 colon cancer cells is due to the induced apoptosis which is caused by the up-regulation of the expression of early apoptotic genes, c-fos & c-jun.

   • Selon Auteur (2016)

     Extrait The results obtained indicate that the root extracts has potent cytotoxic activity toward human colon cancer cells (HCT116). Selected fractions were evaluated for their in vitro anticancer & the crude extract for its antioxidant activity.

3. 3

   Listériose : Listeria monocytogenes

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon LU S (2014)

     Extrait The result of the antimicrobial assay showed that the essential oil displayed varying degrees of antibacterial activity against all tested bacterial except for Pseudomonas aeruginosa, along with minimum inhibition concentration(MIC)values from 39.06 to 252.15 mg/L. The aim of this study was to determine the chemical composition of Synsepalum dulcificum leaf essential oil obtained by steam distillation.

   • Selon Lateef A (2016)

     Extrait Lateef A et al, Phytosynthesis of silver nanoparticles (AgNPs) using miracle fruit plant (Synsepalum dulcificum) for antimicrobial, catalytic, anticoagulant, & thrombolytic applications, DOI: https:/doi.org/10.1515/ntrev-2016-0039,.

   • Selon Afzam Ibrahim H (s.d.)

     Extrait Afzam Ibrahim H et al, Antibacterial Property of Synsepalum dulcificum Leaves Aqueous Extract against Oral Pathogens & Its Chemical Compounds, Archives of Orofacial Sci, 020; 15(1): 55-64,.

   • Selon Auteur (2013)

     Extrait The chemical composition of S dulcificum leaf essential oil obtained by steam distillation was determined & characterized the in vitro antibacterial activity & antitumoral activity of this essential oil. The Synsepalum dulcificum leaf total flavonoid was determined & the Technology & conditions was to be optimum by using the response surface method on the basis of single factor experiment.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.