Syzygium cumini (tété-nègrès) : vertus médicinales en extraction alcoolique

Syzygium cumini (tété-nègrès, Prin-Java, Sein-à-negresse, Prune de Java, Jambolan) — famille Myrtacées.

Synonymes scientifiques : Eugenia caryophyllata-Lam, E. jambolana-Lam, E. cumini-(L)-Druce, Myrtus communis-L, Syzygium jambolanum-(Lam)-(DC.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 35 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 160 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Ulcère gastrique dû au diabète

   Partie usitée : Semence. Association synergique mentionnée : Acarbose.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Jonnalagadda A (2013)

     Extrait The present study evaluated the antidiabetic effects of ethanolic extract of dried seed kernel of Syzygium cumini (200 mg/kg) & its comparative effect on gastric ulcération with standards Acarbose (5 mg/kg) an α-glucosidase inhibitor and natural standard Quercetin 50 mg/kg & 100 mg/kg. It was concluded that S cumini along with Acarbose represents a potential therapeutic option to reduce the risk of Diabetes induced gastric ulcerogenic stimuli in type 2 diabetic patients.

   • Selon Deepa J (2018)

     Extrait To investigate the anti-diabetic activity of combined ethanolic extracts (1:1mixture) of dry leaves of Syzygium cumini & Psidium guajava belonging to the family Myrtaceae as well as to compare the anti-diabetic activity of these plants by in vitro methods .Methods: In vitro glucose uptake assay was performed on cultured L6 cell lines (rat myoblasts cell line) & estimated the glucose uptake using high sensitivity glucose oxidase kit. The percentage inhibition of alpha amylase by the combined ethanolic extract (1:1 mixture) of S cumini & P guajava leaves at a concentration of 1000 µg/ml was 36.51 and it was 29.26 for Syzygium cumini and 23.43 for P guajava.

   • Selon Bangar NS (2025)

     Extrait Result: In vivo experiments using streptozotocin-induced diabetic rats treated with SC preparations exhibited improved biochemical parameters, preserved kidney function, & reduced glycation adduct formation in a dose-dependent manner. Materials & methods: Streptozotocin-induced diabetic rats were treated with SC preparations (200C, 30C, MT; 1:20 dilution in distilled water; 600 μL/kg body weight) & Metformin (45 mg/kg body weight) twice daily for 40 days.

   • Selon ELHAWARY SSE (2022)

     Extrait LC-HR-MS-coupled metabolic profiling of the methanol extracts from different parts of Syzygium cumini (L.), which was extensively identified via DNA fingerprinting, led to dereplication of 24 compounds. Interestingly, the extracts were significant against streptozotocin-induced diabetes in the order of flowers > seeds > leaves with BGL level of 98.9 ± 4.3, 123.2 ± 4.9 and 132.8 ± 5.9 mg/dl, respectively.

   • Selon APTE MM (2024)

     Extrait Syzygium cumini (L.) Skeels (SC), an ancient medicinal plant, is used as a complementary & alternative medicine for treating diabetes mellitus & its associated complications, such as diabetic nephropathy (DN). Additionally, the non-enzymatic formation of advanced glycation & products (AGEs) increases during hyperglycemia in diabetes.

2. 2

   Diabète mellitus de type II

   Partie usitée : Fruit. Association synergique mentionnée : Glimepiride.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon RAZA A (2017)

     Extrait To evaluate the potential of both Jamun (Syzygium cumini) seed & fruit extracts against hyperglycemia. Purposely, Jamun fruit & seed's ethanolic extracts based diets were provided to normal and high sucrose diet induced hyperglycemic/diabetic rats for sixty days.

   • Selon Daulatabad C.M.J (2006)

     Extrait cumini bark, seeds, leaves and fruits are used in the treatment of diabetes, & various extracts have previously shown moderate antibacterial activity against Micrococcus pyogenes.

   • Selon Kumar M (2022)

     Extrait Jamun (Syzygium cumini Skeels) is a nutritious fruit & has historically been used as both as an edible & a traditional medicine. This review paper discusses critically the phytochemical composition of SC seeds & the bioactivities, including their antioxidant, anti-inflammatory, anti-cancer, antidiabetic, anti-microbial, anti-obesity, hepato-protective, cardio & gastro-protective properties.

   • Selon Yadav MM (2009)

     Extrait The combination of most active extracts (200 mg/kg BW) & lower dose of glimepiride (5 mg/kg BW) showed safer & potent hypoglycemic as well as antihyperglycemic activities without creating severe hypoglycemia in normal rats, while higher doses (200 mg/kg bw of most active extracts, & 10 & 20 mg/kg bw of glimepiride) were generated lethal hypoglycemia in normal rats. In present study, we investigated hypoglycemic & antihyperglycemic potential of five extracts (water, ethanol, methanol, hexane, & chloroform) of four plants (i.e., seeds of Eugenia jambolana, fruits of Momordica charantia, leaves of Gymnema sylvestre, & seeds of Trigonella foenumgrecum) alone and/or in combination with glimepiride in rats.

   • Selon Deepa J (2018)

     Extrait To investigate the anti-diabetic activity of combined ethanolic extracts (1:1mixture) of dry leaves of Syzygium cumini & Psidium guajava belonging to the family Myrtaceae as well as to compare the anti-diabetic activity of these plants by in vitro methods .Methods: In vitro glucose uptake assay was performed on cultured L6 cell lines (rat myoblasts cell line) & estimated the glucose uptake using high sensitivity glucose oxidase kit. The percentage inhibition of alpha amylase by the combined ethanolic extract (1:1 mixture) of S cumini & P guajava leaves at a concentration of 1000 µg/ml was 36.51 and it was 29.26 for Syzygium cumini and 23.43 for P guajava.

3. 3

   Cataracte (associée au diabète mellitus de type II)

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Deepa J (2018)

     Extrait To investigate the anti-diabetic activity of combined ethanolic extracts (1:1mixture) of dry leaves of Syzygium cumini & Psidium guajava belonging to the family Myrtaceae as well as to compare the anti-diabetic activity of these plants by in vitro methods .Methods: In vitro glucose uptake assay was performed on cultured L6 cell lines (rat myoblasts cell line) & estimated the glucose uptake using high sensitivity glucose oxidase kit. The percentage inhibition of alpha amylase by the combined ethanolic extract (1:1 mixture) of S cumini & P guajava leaves at a concentration of 1000 µg/ml was 36.51 and it was 29.26 for Syzygium cumini and 23.43 for P guajava.

   • Selon Jonnalagadda A (2013)

     Extrait The study also investigated the combined effect of Syzygium cumini seed kernel extracts with oral hypoglycemic agents in diabetes induced ulcer. The present study evaluated the antidiabetic effects of ethanolic extract of dried seed kernel of Syzygium cumini (200 mg/kg) & its comparative effect on gastric ulcération with standards Acarbose (5 mg/kg) an α-glucosidase inhibitor and natural standard Quercetin 50 mg/kg & 100 mg/kg.

   • Selon Bangar NS (2025)

     Extrait Result: In vivo experiments using streptozotocin-induced diabetic rats treated with SC preparations exhibited improved biochemical parameters, preserved kidney function, & reduced glycation adduct formation in a dose-dependent manner. Materials & methods: Streptozotocin-induced diabetic rats were treated with SC preparations (200C, 30C, MT; 1:20 dilution in distilled water; 600 μL/kg body weight) & Metformin (45 mg/kg body weight) twice daily for 40 days.

   • Selon ELHAWARY SSE (2022)

     Extrait LC-HR-MS-coupled metabolic profiling of the methanol extracts from different parts of Syzygium cumini (L.), which was extensively identified via DNA fingerprinting, led to dereplication of 24 compounds. Interestingly, the extracts were significant against streptozotocin-induced diabetes in the order of flowers > seeds > leaves with BGL level of 98.9 ± 4.3, 123.2 ± 4.9 and 132.8 ± 5.9 mg/dl, respectively.

   • Selon APTE MM (2024)

     Extrait Syzygium cumini (L.) Skeels (SC), an ancient medicinal plant, is used as a complementary & alternative medicine for treating diabetes mellitus & its associated complications, such as diabetic nephropathy (DN). Additionally, the non-enzymatic formation of advanced glycation & products (AGEs) increases during hyperglycemia in diabetes.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.