Tagetes erecta (Œillet d’Inde) : vertus médicinales en extraction alcoolique

Tagetes erecta (Œillet d’Inde, Marigold) — famille Astéracées.

Synonymes scientifiques : Tagetes corymbosa Sweet, T erecta var. erecta, T ernstii H.Rob. & Nicolson, T excelsa Soule, T heterocarpha Rydb., T patula L., T remotiflora Kuntze, T tenuifolia Millsp..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 30 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 108 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Troubles hépatiques : normalisation des paramètres sériques : ALP, GPT, GOT, bilirubine totale, cirrhose, hépatite, stéatose hépatique, nécrose hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Vidyadhar KM (2019)

     Extrait The results showed that the treatment of extract significantly lowered the CCl4induced serum levels of hepatic enzyme markers (GOT, GPT, ALP, total bilirubin Liver histopathology showed that extract reduced the incidence of liver lesions including hepatic cells cloudy swelling, lymphocytes infiltration, hepatic necrosis, & fibrous connective tissue proliferation induced by CCl4 in rats. In this study, the protective effects of water -ethanol extract of TE leaves against liver damage were evaluated in carbon tetrachloride (CCl4) induced chronic hepatotoxicity in rats.

   • Selon Chaniad P (2021)

     Extrait Moreover, no significant alterations in the biochemical parameters of liver & kidney function & no histological changes in the liver or kidney tissues were observed. Biochemical parameters of liver & kidney function & the histopathology of liver & kidney tissues of the acute toxicity group were then examined.

   • Selon NIKKON F (2009)

     Extrait Tagetes erecta has been used in folk medicine for the cure of eye diseases, colds conjunctivitis, rheumatism, coughs, bleeding piles & ulcers. Treatment of chloroform fraction at 200 a&400 mg/kg doses, did not make any significant alterations on the hematological & biochemical parameters of rats when data were compared with that of untreated controls.

   • Selon Kuzhuvelil Bhaskarannair H (2008)

     Extrait Administration of lutein & ester form did not alter the hepatic & renal function, & did not produce any change in the hematological parameters & in lipid profile.

   • Selon Safar A (s.d.)

     Extrait Aim of the study: Considering the lack of scientific studies of TE the present study was aimed to evaluate the chemical composition, antifungal activity of its essential oil against fungi responsible for human infections, as well as its cytotoxicity on HepG2 human liver carcinoma cell lines. T erecta, an important specie from this genus, was widely known for its traditional medicine.

2. 2

   Diabète mellitus de type II

   Partie usitée : Fleur. Profil pharmacologique documenté : Acarbose-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Nunez S (2020)

     Extrait Both types of TE showed lower IC50 values in the α-glucosidase assay than the reference drug acarbose & higher inhibition AGEs formation potential than the reference substance aminoguanidine, they also obtained important values of antiradical activity.The flowers of TE can be considered as source of polyphenol bioactive compounds with interesting properties as functional foods in the prevention & improvement of chronic diseases such as diabetes. Type II diabetes (T2D) is mainly treated with oral antidiabetic drugs.

   • Selon Rodda R (2013)

     Extrait The present study deals with comparative study on anti-diabetic effect of the two ethnomedicinally important plants, Tagetes erecta belongs to the family Compositae & Foeniculum vulgare belongs to the family Umbelliferae in streptozotocin induced diabetic rats. The extract was subjected first to preliminary phytochemical screening, acute toxicity studies and pharmacological screening of anti-diabetic activity in streptozotocin induced diabetic rats.

   • Selon Sathi SI (2012)

     Extrait The results demonstrate that the methanolic extract possesses considerable antihyperglycemic potential, & which is comparable to that of glibenclamide at the highest dose of the extract tested. The antihyperglycemic & antinociceptive potential of Tagetes patula stems, a plant used in folk medicines of Bangladesh for treatment of pain, inflammation, cuts & wounds, & lowering of blood sugar were investigated.

   • Selon Rodda R (2011)

     Extrait Rodda R et al, Antidiabetic potential of Tagetes erecta whole plant in streptozotocin induced diabetic rats.

   • Selon Castañeda R (2023)

     Extrait The most widely studied traditional plants in terms of pharmacological evidence, bioactive compounds, & mechanisms of action, are Annona muricata L., Carica papaya L., Ipomoea batatas (L.) Lam., Lantana camara L., Sechium edule (Jacq.) Sw., Tagetes erecta L., & Zea mays L. A total of 208 plants used for kidney-related problems by 10 Mayan groups were found, representing 143 native species, where only 42 have reported pharmacological activity against kidney damage, mainly approached by in vitro & in vivo models of chemical- or drug-induced nephrotoxicity, diabetes nephropathy, & renal injury produced by hypertension.

3. 3

   Cancer : traitement adjuvant du carcinome colorectal, hépatique

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Chaniad P (2021)

     Extrait To investigate the antimalarial effects and toxicity of the extracts of the flowers of Tagetes erecta L. Moreover, no significant alterations in the biochemical parameters of liver & kidney function & no histological changes in the liver or kidney tissues were observed.

   • Selon Vidyadhar KM (2019)

     Extrait In this study, the protective effects of water -ethanol extract of TE leaves against liver damage were evaluated in carbon tetrachloride (CCl4) induced chronic hepatotoxicity in rats. The results showed that the treatment of extract significantly lowered the CCl4induced serum levels of hepatic enzyme markers (GOT, GPT, ALP, total bilirubin Liver histopathology showed that extract reduced the incidence of liver lesions including hepatic cells cloudy swelling, lymphocytes infiltration, hepatic necrosis, & fibrous connective tissue proliferation induced by CCl4 in rats.

   • Selon Meurer MC (2019)

     Extrait Given the role of oxidative stress in ulcerative colitis (UC) etiology & the amount of lutein (a carotenoid with antioxidant properties) in the dry hydroalcoholic extract of Tagetes erecta flowers (DHETE), this study investigated the intestinal anti-inflammatory properties of DHETE in an animal model of UC. The treatment with DHETE decreased myeloperoxidase activity as well as tumor necrosis factor & interleukin-6 levels.

   • Selon Kumar R (2010)

     Extrait Lutein is found in many plants, but the purest & richest source is the petals of marigold flowers (Tagetes erecta L.). Lutein is associated with the prevention of many chronic diseases, like age-related macular degeneration, cancer & cardiovascular diseases.

   • Selon Gonzalez ASC (2023)

     Extrait Tagetes erecta is a plant of great cultural value, & recent reports have suggested its cytotoxic effects in tumor cells. In vivo, a xenograft lung carcinoma model was performed with LLC cells implanted on C57BL/6 mice, which showed that the floral extract reduced tumor growth & improved the effect of etoposide.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.