Taraxacum officinale (Pisanli) : vertus médicinales en extraction alcoolique

Taraxacum officinale (Pisanli, Pissenlit, Dent-de-lion, Dandelion) — famille Astéracées.

Synonymes scientifiques : Crepis taraxacum (L.) Stokes, Leontodon taraxacum L., Taraxacum campylodes G.E.Haglund, T dens-Leonis-Desv, Tofficinale (L.) Weber ex F. H. Wigg., T subspathulatum A.J.Richards, T vulgare (Lam.) Shrank.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 10 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 140 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Chungmu P (2010)

     Extrait in this work, we estimate the inhibitory effect of two polysaccharides from Taraxacum officinale (TOP) on CCl4-induced oxidative stress & inflammation in Sprague–Dawley rats. TOPs pretreatment also reversed other hepatitis-associated symptoms, including GSH depletion, inhibited anti-oxidative enzyme activities, up-regulation of NF-κB & increased expression of its regulatory inflammatory mediators, such as inducible nitric oxide synthase (iNOS), cyclooxygenase (COX)-2, tumor necrosis factor(TNF)-α, & interleukin (IL)-1β.

   • Selon Hamza A.A (2020)

     Extrait the study was conducted to evaluate the effects of whole plant powder of dandelion (Taraxacum officinale) on liver fibrosis. The total antioxidant study of TO extract revealed that TO has notable ferric reducing antioxidant power and high total phenolic content.Conclusion : Finally, these results suggest that dandelion prevents the progression of hepatic fibrosis induced by CCL4.

   • Selon Domitrović, R (2010)

     Extrait Conclusions : Our results suggest the therapeutic effect of DWE on CCl4-induced liver fibrosis by the inactivation of hepatic stellate cells & the enhancement of hepatic regenerative capabilities. The present study was aimed to assess the efficacy of dandelion root water–ethanol extract (DWE) in carbon tetrachloride (CCl4)-induced hepatic fibrosis.

   • Selon Pfingsgraf LO (2021)

     Extrait Taraxacum officinale (TO) or dandelion has been frequently used to prevent or treat different liver diseases because of its rich composition in phytochemicals with demonstrated effect against hepatic injuries. This study aimed to investigate the possible preventing effect of ethanolic TO root extract (TOERE) on a rat experimental acute on chronic liver failure (ACLF) model.

   • Selon Davaatseren M (2013)

     Extrait The purpose of this study is to determine the protective effect of Taraxacum official(dandelion) leaf extract (DLE) on high-fat-diet (HFD)-induced hepatic steatosis, & elucidate the molecular mechanisms behind its effects. Body & liver weights of the DL & DH groups were significantly lesser than those of the HFD group, and DLE supplementation dramatically suppressed triglyceride (TG), total cholesterol (TC), insulin, fasting glucose level in serum, & Homeostatic Model Assessment Insulin Resistance (HOMA-IR) induced by HFD.

2. 2

   Diabète mellitus de type II, association synergique avec l’extrait de feuille

   Partie usitée : Racine.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sharma M (2023) — extrait

     Extrait Taraxacum officinale play an important role in the prophylaxis & treatment of cardiovascular disease (CVD). This study not only explored the overall cardioprotective potential but also tried to explore its molecular mechanism using pharmacological inhibition via L-NAME & glibenclamide.

   • Selon Ricky DC (2019) — extrait

     Extrait This study uses True Experimental Design, 22 male rats are divided into five groups: Negative Control (Group I), Positive Control (group II), Experiment I (group III): Rats were induced by alloxan and given extracted jombang leaves orally as much as 0.4 ml (0.65 gram), 0.6 ml (0.97 gram), and 0.8 ml (1.29gram), Experiment II (group IV): Rats were induced by alloxan & given extracted jombang roots orally as much as 0.4 ml (0.77 grams), 0.6 ml (1.15 grams) & 0.8 ml (1.54 grams) & Experiment III (Group v): Rats were induced by alloxan & given extracted as much mixture of leaves & roots of TO 0.4 ml (0.71 gram), 0.6 ml (1.06 gram) and 0.8 ml (1.42 gram). The result showed that the volume of group leaf extract, robot extract and the mixture of leaf & root extract 0.4 ml (0.65 g), 0.6 ml (0.97 g), and 0.8 ml (1.29 ml) can reducing blood glucose levels in alloxan-induced ratsat the end of the Study.

   • Selon Frag MR (2022) — extrait

     Extrait Taraxacum officinale, also known as dandelion herb, is a popular medicinal and therapeutic herb used for many years and is mostly raised in Europe, Asia, North & South America. This herb also has various beneficial functions, such as immunomodulatory effects, stimulation of the digestive system & insulin activation, enhancing the metabolism of androgens, & acting as a probiotic, antiangiogenic, antineoplastic & demulcent.

   • Selon Davaatseren M (2013) — extrait

     Extrait Body & liver weights of the DL & DH groups were significantly lesser than those of the HFD group, and DLE supplementation dramatically suppressed triglyceride (TG), total cholesterol (TC), insulin, fasting glucose level in serum, & Homeostatic Model Assessment Insulin Resistance (HOMA-IR) induced by HFD. The purpose of this study is to determine the protective effect of Taraxacum official(dandelion) leaf extract (DLE) on high-fat-diet (HFD)-induced hepatic steatosis, & elucidate the molecular mechanisms behind its effects.

   • Selon Wirngo FE (2016) — extrait

     Extrait This review recapitulates previous work on dandelion & its potential for the treatment & prevention of T2D, highlighting its anti-diabetic properties, the structures of its chemical components, & their potential mechanisms of action in T2D. The anti-diabetic properties of dandelion are attributed to bioactive chemical components; these include chicoric acid, taraxasterol (TS), chlorogenic acid, & sesquiterpene lactones.

3. 3

   Diabète mellitus de type II : association synergique avec l’extrait de racine

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sharma M (2023) — extrait

     Extrait Taraxacum officinale play an important role in the prophylaxis & treatment of cardiovascular disease (CVD). This study not only explored the overall cardioprotective potential but also tried to explore its molecular mechanism using pharmacological inhibition via L-NAME & glibenclamide.

   • Selon Ricky DC (2019) — extrait

     Extrait This study uses True Experimental Design, 22 male rats are divided into five groups: Negative Control (Group I), Positive Control (group II), Experiment I (group III): Rats were induced by alloxan and given extracted jombang leaves orally as much as 0.4 ml (0.65 gram), 0.6 ml (0.97 gram), and 0.8 ml (1.29gram), Experiment II (group IV): Rats were induced by alloxan & given extracted jombang roots orally as much as 0.4 ml (0.77 grams), 0.6 ml (1.15 grams) & 0.8 ml (1.54 grams) & Experiment III (Group v): Rats were induced by alloxan & given extracted as much mixture of leaves & roots of TO 0.4 ml (0.71 gram), 0.6 ml (1.06 gram) and 0.8 ml (1.42 gram). The result showed that the volume of group leaf extract, robot extract and the mixture of leaf & root extract 0.4 ml (0.65 g), 0.6 ml (0.97 g), and 0.8 ml (1.29 ml) can reducing blood glucose levels in alloxan-induced ratsat the end of the Study.

   • Selon Davaatseren M (2013) — extrait

     Extrait Body & liver weights of the DL & DH groups were significantly lesser than those of the HFD group, and DLE supplementation dramatically suppressed triglyceride (TG), total cholesterol (TC), insulin, fasting glucose level in serum, & Homeostatic Model Assessment Insulin Resistance (HOMA-IR) induced by HFD. The purpose of this study is to determine the protective effect of Taraxacum official(dandelion) leaf extract (DLE) on high-fat-diet (HFD)-induced hepatic steatosis, & elucidate the molecular mechanisms behind its effects.

   • Selon Frag MR (2022) — extrait

     Extrait Taraxacum officinale, also known as dandelion herb, is a popular medicinal and therapeutic herb used for many years and is mostly raised in Europe, Asia, North & South America. This herb also has various beneficial functions, such as immunomodulatory effects, stimulation of the digestive system & insulin activation, enhancing the metabolism of androgens, & acting as a probiotic, antiangiogenic, antineoplastic & demulcent.

   • Selon Wirngo FE (2016) — extrait

     Extrait This review recapitulates previous work on dandelion & its potential for the treatment & prevention of T2D, highlighting its anti-diabetic properties, the structures of its chemical components, & their potential mechanisms of action in T2D. The anti-diabetic properties of dandelion are attributed to bioactive chemical components; these include chicoric acid, taraxasterol (TS), chlorogenic acid, & sesquiterpene lactones.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.