Tephrosia purpurea (Lannivraj) : vertus médicinales en extraction alcoolique

Tephrosia purpurea (Lannivraj, Digo-savann, Ennivrage, Indigo-à-savane) — famille Fabacées.

Synonymes scientifiques : Cracca purpurea-L., Tephrosia lanceifolia-Link., T leptostachya-DC..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 32 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 139 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer: chemoprevention du carcinome hépatique

   Partie usitée : Racine.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Hussain T (2012)

     Extrait The chemopreventive potential of Tephrosia purpurea extract (TPE) on N-nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma (HCC) in Wistar rats was assessed. Conclusions :These findings powerfully support that TP prevented lipid peroxidation, suppressed the tumour burden, & promoted enzymatic & nonenzymatic antioxidant defence systems during NDEA-induced hepatocarcinogenesis.

   • Selon Gnana-raja R (2014)

     Extrait The aim of the present study is to divulge the preventive nature of Tephrosia purpurea Methanolic Extract (TpME) during DiEthylNitrosAmine (DENA) induced liver cancer in male Swiss albino mice. Anticancer activity of methanolic extract of Tephrosia purpurea was evaluated in DENA induced Swiss albino mice at the doses of 200 and 300 mg/kg body weight orally and both doses were administered for 14 days.

   • Selon Padmapriya R (2017)

     Extrait Tephrosia purpurea is an Indian herb used in traditional medicine to treat various diseases such as jaundice, asthma, liver & urinary disorders. Therefore, this study aims to investigate the anti-cancer activity of TP in HepG2 hepatocellular carcinoma cells.

   • Selon Gnanaraja R (2015)

     Extrait The maximum reduction of liver cancer marker & antioxidant marker were found formulated drug from TP as well as histopathology studies were exhibited maximum improvement against hepatocellular carcinoma. TThe drugs from Tephrosia purpurea to provide new & important leads against various pharmacological targets against cancer & other diseases.

   • Selon Hussain T (2012)

     Extrait The chemopreventive potential of Tephrosia purpurea extract (TPE) on N-nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma (HCC) in Wistar rats was assessed. Conclusions: These findings powerfully support that TP prevented lipid peroxidation, suppressed the tumour burden, & promoted enzymatic & nonenzymatic antioxidant defense systems during NDEA-induced hepatocarcinogenesis.

2. 2

   Cataracte sénile liée au diabète

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon BHADADA (2016)

     Extrait Tephrosia purpurea has been reported to prevent cataract formation in senile cataract model as well as proven effective in STZ induced type 1 diabetes. Methods : We studied the effects of alcoholic extract and flavonoid fraction of TP in streptozotocin (STZ, 45 mg/kg, i.v.)-induced type I diabetic cataract in rats.

   • Selon BHADADA S (2015)

     Extrait BHADADA S et al, Effect of Aqueous Extract of Tephrosia purpurea on Cardiovascular Complications and Cataract Associated with Streptozotocin-induced Diabetes in Rats Indian J of Pharmaceut Sci, 2015-DOI: 10.4103/0250-474X.169037 (43),.

   • Selon Arora SK (2021)

     Extrait purpurea), commonly known as Sarpunkha has been used in traditional systems of medicine to treat diabetes mellitus. purpurea leaves extract, its fractions & main constituent Rutin in diabetic rats.

   • Selon Pavana P (2017)

     Extrait In this experiment, authors evaluated the beneficial role of Tephrosia purpurea Ethanolic seed extract [TpEt] standard (normal) versus streptozotocin [STZ] induced diabetic male albino wistar rats & studied the membrane stabilizing effects of TpEt in diabetic male albino rats. Diabetes mellitus was induced by giving streptozotocin intraperitoneally & blood glucose of above 250 mg/dl was considered diabetes.

   • Selon Singh V (2008)

     Extrait Flavonoids are present widely in Angiospermic plants & are associated with several pharmacological activities including antibacterial, antidiabetic, antifungal, anti-allergic & anti-oxidant activities.

3. 3

   Diabète mellitus de type II

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Arora SK (2021)

     Extrait purpurea), commonly known as Sarpunkha has been used in traditional systems of medicine to treat diabetes mellitus. purpurea leaves extract, its fractions & main constituent Rutin in diabetic rats.

   • Selon Pavana P (2017)

     Extrait In this experiment, authors evaluated the beneficial role of Tephrosia purpurea Ethanolic seed extract [TpEt] standard (normal) versus streptozotocin [STZ] induced diabetic male albino wistar rats & studied the membrane stabilizing effects of TpEt in diabetic male albino rats. Diabetes mellitus was induced by giving streptozotocin intraperitoneally & blood glucose of above 250 mg/dl was considered diabetes.

   • Selon BHADADA (2016)

     Extrait Tephrosia purpurea has been reported to prevent cataract formation in senile cataract model as well as proven effective in STZ induced type 1 diabetes. Methods : We studied the effects of alcoholic extract and flavonoid fraction of TP in streptozotocin (STZ, 45 mg/kg, i.v.)-induced type I diabetic cataract in rats.

   • Selon Singh V (2008)

     Extrait Flavonoids are present widely in Angiospermic plants & are associated with several pharmacological activities including antibacterial, antidiabetic, antifungal, anti-allergic & anti-oxidant activities.

   • Selon PAMU P (2017)

     Extrait Diabetes mellitus was induced by giving streptozotocin intraperitoneally and blood glucose of above 250 mg/dl was considered diabetes. In this experiment, authors evaluated the beneficial role of TP Ethanolic seed extract [Tp Et] standard (normal) versus streptozotocin [STZ] induced diabetic male albino Wistar rats & studied the membrane stabilizing effects of Tp Et in diabetic male albino rats.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.