Thymus vulgaris (Diten-frans) : vertus médicinales en extraction alcoolique

Thymus vulgaris (Diten-frans, Ti-diten, Thym de France, Petit thym, French thyme, Small thyme) — famille Lamiacées.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 24 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 106 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome prostatique, pulmonaire et de la leucémie

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Jaafari A (2007)

     Extrait vulgaris has effective anticancer activity against human lung cancer cells and Human prostate cancer cells and hence could be a potential source of chemotherapeutics for treatment of cancer. The samples were tested for possible anticancer activity by using MTT assay on Human lung(A549) and prostate Cancer (IGR-CAP1) Cell Lines The results of these studies have shown that the ethanolic extract T.

   • Selon Soomro S (2019)

     Extrait Furthermore, for anticancer potential butanol fraction was found to be slightly effective against HeLa cancer cells with percent inhibition of 25%. The current studies are aiming to further explore the phytoconstituents of Thymus vulgaris & its biological activity.

   • Selon Zeng Q (2020)

     Extrait Increasing evidence has indicated that thymol exerts prominent antitumor effects in a variety of cancers, including CRC. Colorectal cancer (CRC) is one of the most commonly occurring cancers & is associated with high morbidity & mortality.

   • Selon Sertel S (2011)

     Extrait Sertel S et al: Cytotoxicity of Thymus vulgaris essential oil towards human oral cavity squamous cell carcinoma. However, it is unknown whether the medicinal plant Thymus vulgaris L.

   • Selon Ayesh (2014)

     Extrait Methods : Ethanol extracts were prepared from Thymus vulgaris. vulgaris represents a potential selective cytostatic & safe target for future anticancer agents’ development.

2. 2

   Infection bactérienne : Staphylococcus aureus, Bacillus Cereus, Shigella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Auteur (2008)

     Extrait Essential oils (EOs) & methanol extracts obtained from aerial parts of Thymus vulgaris & Pimpinella anisum seeds were evaluated for their single & combined antibacterial activities against nine Gram-positive & Gram-negative pathogenic bacteria: Staphylococcus aureus, Bacillus cereus, Escherichia coli, Proteus vulgaris, Proteus mirabilis, Salmonella typhi, Salmonella typhimurium, Klebsiella pneumoniae & Pseudomonas aeruginosa. Maximum activity of TV & PA essential oils & methanol extracts (MIC 15.6 & 62.5mug/ml) were observed against Staphylococcus aureus, Bacillus cereus & Proteus vulgaris.

   • Selon Mathkoor MM (2024)

     Extrait It evaluated their ability to inhibit pathogenic & antibiotic-resistant bacteria, including Staphylococcus aureus (S.aureus), Pseudomonas aeruginosa (P aeruginosa),& Escherichia coli (E.coli) isolated from skin ulcers. P.aeruginosa was very weak compared to the effectiveness of these EOs o other bacterial species used in the study, where the highest diameter of inhibition of these bacteria was by SA oil & reached 15 mm.

   • Selon Micucci M (2020)

     Extrait The solid EO exhibits antimicrobial activity against different strains (Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, Escherichia coli, Salmonella Thyphimurium, Candida albicans) similarly to liquid oil, with activity against pathogen, but not commensal strains (Bifidobacterium Breve, Lactobacillus Fermentum) in intestinal homeostasis. A new Thymus vulgaris L.

   • Selon TAHA SM (2024)

     Extrait This study aimed to evaluate the antimicrobial, antioxidant, & immunomodulatory activities of Lagenaria siceraria, Thymus vulgaris, & their chitosan nanocomposites against extensive drug-resistant (XDR) Pseudomonas aeruginosa & vancomycin-resistant Staphylococcus aureus (VRSA) using both in vitro & in vivo assays. These values returned to the normal range after treatment by chitosan nanoparticles, either loaded with Lagenaria siceraria or Thymus vulgaris.

   • Selon Soomro S (2019)

     Extrait Our results demonstrated that ethanolic extract of TV possesses significant activity against Salmonella typhi, Staphylococcus aureus, & Bacillus subtilis. The current studies are aiming to further explore the phytoconstituents of Thymus vulgaris & its biological activity.

3. 3

   Arthrose, arthrite, rhumatisme, œdème

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Vassiliou E (2023)

     Extrait Thymus comprises numerous molecular species exhibiting diverse therapeutic properties that are dependent on their biologically active concentrations in the extracted oil. Furthermore, the phenophase of the same plant species has been shown to yield different anti-inflammatory properties.

   • Selon Ocaña A (2012)

     Extrait Properties of thyme extracts from three different species (Thymus vulgaris, Thymus zygis & Thymus hyemalis) were examined. Thyme extracts significantly reduced production & gene expression of the proinflammatory mediators TNF-α, IL-1B & IL-6 & highly increased these parameters on the anti-inflammatory IL-10 cytokine.

   • Selon SHALLANGW AGA (2012)

     Extrait These findings showed that both Moringa oleifera and Thymus vulgaris possessed marked in vitro antiinflammatory effect against the denaturation of protein when compared with the standard anti-inflammatory drug, Ibuprofen. The aim of the present study is to evaluate and compare thein vitro anti-inflammatory effects of ethanol extracts of M oleifera and T vulgaris and a 1:1 blend of the two extracts against the denaturation of proteins.

   • Selon Auteur (2017)

     Extrait The Thymus vulgaris extracts are effective as anti-inflammatory, Immunomodulatory, antioxidant, antibacterial and antifungal. coli); (2) negative control (without infection); and treatment groups T1, T2, T3 (infected mice administrated with ethanol extract of Thymus vulgaris (ETV) 250, 500, 750 mg/kg B.wt).

   • Selon Soomro S (2019)

     Extrait The current studies are aiming to further explore the phytoconstituents of Thymus vulgaris & its biological activity. Thymus vulgaris (za‟atar) is one of the most famous and traditional spices of Arab countries.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.