Trigonella foenum (Fenugrec) : vertus médicinales en extraction alcoolique

Trigonella foenum (Fenugrec) — famille Fabacées.

Synonymes scientifiques : Foenum-graecum officinale, var Tibetanum-Alef, Trigonella tibetana-(A)-Vass..

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 19 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 157 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type I

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Gupta M (2018)

     Extrait Alloxan (dissolved in 0.1 M citrate buffer (pH = 4.5); intraperitoneally injected @ 130 mg/kg body weight) induced type I diabetic rats were treated with individual & combined doses of ethanol extracts of CQ & TFG for consecutive 30 days @ 250 & 500 mg per kg body weight, orally. CQ & TFG combination therapy showed a marked improvement in bone microarchitecture & can be given together as a potential alternative medicine to insulin for prevention of type I diabetes induced osteopathy.

   • Selon Bafadam S (2020)

     Extrait Bafadam S et al, Trigonella foenum-graceum seed (Fenugreek) hydroalcoholic extract improved the oxidative stress status in a rat model of diabetes-induced memory impairment, Horm Mol Biol Invest, 2020-Abstrac: The antidiabetic & antioxidant effects of Trigonella foenum-graceum have been suggested. foenum-graceum seed prevented memory deficits resulting from diabetes.

   • Selon Yadav MM (2009)

     Extrait In present study, we investigated hypoglycemic & antihyperglycemic potential of five extracts (water, ethanol, methanol, hexane, & chloroform) of four plants (i.e., seeds of Eugenia jambolana, fruits of Momordica charantia, leaves of Gymnema sylvestre, & seeds of Trigonella foenum graecum) alone and/or in combination with glimepiride in rats. The combination of most active extracts (200 mg/kg BW) & lower dose of glimepiride (5 mg/kg BW) showed safer & potent hypoglycemic as well as antihyperglycemic activities without creating severe hypoglycemia in normal rats, while higher doses (200 mg/kg bw of most active extracts, & 10 & 20 mg/kg bw of glimepiride) were generated lethal hypoglycemia in normal rats.

   • Selon Abdel-Barry JA (1997)

     Extrait The aqueous & alcoholic extracts of Trigonella foenum-graecum leaf were tested for hypoglycaemic activity in normal and alloxan-diabetic rats. & 1, 2, 8 g/kg, p.o.) of the aqueous extract of Trigonella foenum-graecum leaf when given to both normal & alloxan-diabetic rats, a significant reduction of blood glucose concentration was noticed.

   • Selon Singh P (2014)

     Extrait The plant Trigonella foenum-graceum (TFG) is used as antidiabetic & diuretic.

2. 2

   Trouble mnésique associé au diabète

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Bafadam S (2020)

     Extrait Bafadam S et al, Trigonella foenum-graceum seed (Fenugreek) hydroalcoholic extract improved the oxidative stress status in a rat model of diabetes-induced memory impairment, Horm Mol Biol Invest, 2020-Abstrac: The antidiabetic & antioxidant effects of Trigonella foenum-graceum have been suggested. foenum-graceum seed prevented memory deficits resulting from diabetes.

   • Selon Yadav MM (2009)

     Extrait In present study, we investigated hypoglycemic & antihyperglycemic potential of five extracts (water, ethanol, methanol, hexane, & chloroform) of four plants (i.e., seeds of Eugenia jambolana, fruits of Momordica charantia, leaves of Gymnema sylvestre, & seeds of Trigonella foenum graecum) alone and/or in combination with glimepiride in rats. The combination of most active extracts (200 mg/kg BW) & lower dose of glimepiride (5 mg/kg BW) showed safer & potent hypoglycemic as well as antihyperglycemic activities without creating severe hypoglycemia in normal rats, while higher doses (200 mg/kg bw of most active extracts, & 10 & 20 mg/kg bw of glimepiride) were generated lethal hypoglycemia in normal rats.

   • Selon Abdel-Barry JA (1997)

     Extrait The aqueous & alcoholic extracts of Trigonella foenum-graecum leaf were tested for hypoglycaemic activity in normal and alloxan-diabetic rats. & 1, 2, 8 g/kg, p.o.) of the aqueous extract of Trigonella foenum-graecum leaf when given to both normal & alloxan-diabetic rats, a significant reduction of blood glucose concentration was noticed.

   • Selon Gupta M (2018)

     Extrait Alloxan (dissolved in 0.1 M citrate buffer (pH = 4.5); intraperitoneally injected @ 130 mg/kg body weight) induced type I diabetic rats were treated with individual & combined doses of ethanol extracts of CQ & TFG for consecutive 30 days @ 250 & 500 mg per kg body weight, orally. CQ & TFG combination therapy showed a marked improvement in bone microarchitecture & can be given together as a potential alternative medicine to insulin for prevention of type I diabetes induced osteopathy.

   • Selon Singh P (2014)

     Extrait The plant Trigonella foenum-graceum (TFG) is used as antidiabetic & diuretic.

3. 3

   Diabète mellitus de type II

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Bafadam S (2020)

     Extrait Bafadam S et al, Trigonella foenum-graceum seed (Fenugreek) hydroalcoholic extract improved the oxidative stress status in a rat model of diabetes-induced memory impairment, Horm Mol Biol Invest, 2020-Abstrac: The antidiabetic & antioxidant effects of Trigonella foenum-graceum have been suggested. foenum-graceum seed prevented memory deficits resulting from diabetes.

   • Selon Yadav MM (2009)

     Extrait In present study, we investigated hypoglycemic & antihyperglycemic potential of five extracts (water, ethanol, methanol, hexane, & chloroform) of four plants (i.e., seeds of Eugenia jambolana, fruits of Momordica charantia, leaves of Gymnema sylvestre, & seeds of Trigonella foenum graecum) alone and/or in combination with glimepiride in rats. The combination of most active extracts (200 mg/kg BW) & lower dose of glimepiride (5 mg/kg BW) showed safer & potent hypoglycemic as well as antihyperglycemic activities without creating severe hypoglycemia in normal rats, while higher doses (200 mg/kg bw of most active extracts, & 10 & 20 mg/kg bw of glimepiride) were generated lethal hypoglycemia in normal rats.

   • Selon Abdel-Barry JA (1997)

     Extrait The aqueous & alcoholic extracts of Trigonella foenum-graecum leaf were tested for hypoglycaemic activity in normal and alloxan-diabetic rats. & 1, 2, 8 g/kg, p.o.) of the aqueous extract of Trigonella foenum-graecum leaf when given to both normal & alloxan-diabetic rats, a significant reduction of blood glucose concentration was noticed.

   • Selon Gupta M (2018)

     Extrait Alloxan (dissolved in 0.1 M citrate buffer (pH = 4.5); intraperitoneally injected @ 130 mg/kg body weight) induced type I diabetic rats were treated with individual & combined doses of ethanol extracts of CQ & TFG for consecutive 30 days @ 250 & 500 mg per kg body weight, orally. CQ & TFG combination therapy showed a marked improvement in bone microarchitecture & can be given together as a potential alternative medicine to insulin for prevention of type I diabetes induced osteopathy.

   • Selon Singh P (2014)

     Extrait The plant Trigonella foenum-graceum (TFG) is used as antidiabetic & diuretic.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.