Uncaria guianensis (Grif-chat) : vertus médicinales en extraction alcoolique

Uncaria guianensis (Grif-chat, Griffe-à-chat, Cat scratcher) — famille Rubiacées.

Synonymes scientifiques : Nauclea aculeata (Willd.) Willd., N guianensis (Aubl.) Poir., Ourouparia guianensis Aubl. Uncaria aculeata Willd. U spinosa Raeusch.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 7 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 21 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome mammaire

   Partie usitée : Écorce.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Rahmawati N (2023)

     Extrait This study aims to determine the cytotoxic effect of ethanolic extract from the leaves & stem bark of Uncaria Spp on T47D breast cancer cells. The ethanolic extract of U nervosa leaves had a strong cytotoxic effect on T47D breast cancer cells, which was 64.42 µg/mL.

   • Selon Urdanibia I (2013)

     Extrait Uncaria guianensis (Aublet) Gmel (Rubiaceae) is a medicinal plant from the jungles of South & Central America, used to treat cancer, arthritis, diabetes, & inflammation. Materials & methods: Bio-guided fractionation of a hydroethanolic extract of UG was performed, evaluating the fractions & subfractions for their effect on inflammatory mediators, tumour necrosis factor alpha (TNF-α), interleukin 6 (IL-6) & prostaglandin E2 (PGE2) by ELISA & nitric oxide (NO) by the Griess reaction in cultured supernatant from RAW 264.7 macrophages stimulated with lipopolysaccharide (LPS).

   • Selon Paixão D (2021)

     Extrait The Amazonian Rubiaceae species Uncaria guianensis (UG) is locally used as anti-inflammatory, antitumor, antidiabetic, anti-ulcers, & others.

2. 2

   Inflammation : arthrose, arthrite, rhumatisme, œdème

   Partie usitée : Écorce.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Carvalho MC (2006)

     Extrait Carvalho MC et al, Investigations on the anti-inflammatory & anti-allergic activities of the leaves of Uncaria guianensis (Aublet) J. We investigated the anti-inflammatory & antiallergic properties of an ethanolic extract of UG leaves, containing alkaloids, flavonoids & phenol carboxylic acids, as revealed by thin layer chromatography (TLC).

   • Selon Miller (2004)

     Extrait Cartilage degradation, a hallmark of both rheumatoid arthritis & osteoarthritis, contributes to the dysmobility, pain & compromised quality of life associated with these conditions. Vincaria, an alkaloid depleted aqueous extract of cat’s claw (Uncaria guianensis) was studied in combination with SierraSil (final concentra- tions of 2.5, 5 & 10 ng/ml).

   • Selon Urdanibia I (2013)

     Extrait Uncaria guianensis (Aublet) Gmel (Rubiaceae) is a medicinal plant from the jungles of South & Central America, used to treat cancer, arthritis, diabetes, & inflammation. The effect of UG on the inflammatory response in vivo was assessed in BALB/c mice stimulated with LPS, on rat paw oedema induced by carrageenan, & on tumour growth & lung metastasis in BALB/c mice inoculated with 4T1 mammary tumour cells.

   • Selon Piscoya J (2001)

     Extrait The purpose of this investigation was to evaluate the ability of cat's claw, an Amazonian medicinal plant, to treat osteoarthritis of the knee, collect safety & tolerance information & compare the antioxidant, & anti-inflammatory actions of Uncaria guianensis & Uncaria tomentosa in vitro. Materials & methods: Forty-five patients with osteoarthritis of the knee were recruited, 30 were treated with freeze-dried U guianensis, & 15 with placebo.

   • Selon Da Silva Zanetti L (2020)

     Extrait Uncaria guianensis (Aubl.) J. (“cat’s claw”, Rubiaceae) is a plant with potential to treat asthma because of its anti-inflammatory & antioxidant activities.

3. 3

   Arthrose, arthrite, rhumatisme, œdème

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Carvalho MC (2006)

     Extrait Carvalho MC et al, Investigations on the anti-inflammatory & anti-allergic activities of the leaves of Uncaria guianensis (Aublet) J. We investigated the anti-inflammatory & antiallergic properties of an ethanolic extract of UG leaves, containing alkaloids, flavonoids & phenol carboxylic acids, as revealed by thin layer chromatography (TLC).

   • Selon Miller (2004)

     Extrait Cartilage degradation, a hallmark of both rheumatoid arthritis & osteoarthritis, contributes to the dysmobility, pain & compromised quality of life associated with these conditions. Vincaria, an alkaloid depleted aqueous extract of cat’s claw (Uncaria guianensis) was studied in combination with SierraSil (final concentra- tions of 2.5, 5 & 10 ng/ml).

   • Selon Piscoya J (2001)

     Extrait The purpose of this investigation was to evaluate the ability of cat's claw, an Amazonian medicinal plant, to treat osteoarthritis of the knee, collect safety & tolerance information & compare the antioxidant, & anti-inflammatory actions of Uncaria guianensis & Uncaria tomentosa in vitro. Materials & methods: Forty-five patients with osteoarthritis of the knee were recruited, 30 were treated with freeze-dried U guianensis, & 15 with placebo.

   • Selon Urdanibia I (2013)

     Extrait Uncaria guianensis (Aublet) Gmel (Rubiaceae) is a medicinal plant from the jungles of South & Central America, used to treat cancer, arthritis, diabetes, & inflammation. The effect of UG on the inflammatory response in vivo was assessed in BALB/c mice stimulated with LPS, on rat paw oedema induced by carrageenan, & on tumour growth & lung metastasis in BALB/c mice inoculated with 4T1 mammary tumour cells.

   • Selon Da Silva Zanetti L (2020)

     Extrait Uncaria guianensis (Aubl.) J. (“cat’s claw”, Rubiaceae) is a plant with potential to treat asthma because of its anti-inflammatory & antioxidant activities.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.