Urena lobata (Gran Maho-Kouzen) : vertus médicinales en extraction alcoolique

Urena lobata (Gran Maho-Kouzen, Kouzen-wouj, Kouzen Maho, Grand Mahaut-cousin, Cousin rouge, Cousin-Mahaut, Red cousin) — famille Malvacées.

Synonymes scientifiques : Urena americana-L. f, U grandiflora-DC, U. Lobata-Vell, U. lobata-L, var. americana- (L.f)-Gürke..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 8 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 49 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Purnomo Y (2015)

     Extrait Urena lobata is a plant which has been used to cure T2DM empirically but the inhibitory activity on DPP-IV has not been tested. Both of water & ethanolic extract from UL decrease DPP-IV level & blood glucose AUC compared to control group (p<0.05) whereas insulin level & GLP-1 are increased (p<0.05).

   • Selon Yudi P (2015)

     Extrait To evaluate the antidiabetic potential of leaf extract from Urena lobata (U. lobata showed stronger DPP-IV inhibitor activity than water extract with the IC50 values of 1 654.64 & 6 489.88 μg/mL, respectively.

   • Selon Islam H (2015)

     Extrait In oral glucose tolerance tests with methanolic extract of Urena lobata leaves (MEUL), the extract significantly & dose-dependently reduced blood glucose concentrations in glucose-loaded mice. In comparison, a standard antihyperglycemic drug, glibenclamide, when administered at a dose of 10 mg per kg, reduced blood glucose level by 61.2%.

   • Selon OMONKHUA AA (2011)

     Extrait Urena lobata is one of the medicinal plants used to treat diabetes in Nigeria. Its hypoglycaemic & anti- diabetic activities have been demonstrated.

   • Selon Onoagbe IO (2010)

     Extrait Onoagbe IO et al, A study of the Anti-diabetic effects of Urena lobata & Sphenostylis stenocarpa in streptozotocin-induced diabetic rats, Eur J Sci Res, 43 (1) (2010), 6-14.

2. 2

   Cancer: traitement adjuvant du carcinome epidermoide

   Partie usitée : Feuille. Profil pharmacologique documenté : Taxotere-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Pieme CA (2012)

     Extrait Pieme CA et al, In vitro antiproliferative & anti-oxidant activities of methanol extracts of Urena lobata & Viscum album against breast cancer cell lines Toxicol & Environ Chem, 2012-DOI: 10.1080/02772248.2012.674135,.

   • Selon MAKANBILA MC (2011)

     Extrait Thirty-three extracts were obtained in 3 different solvents (Water, Ethanol, DCM) from these ten plants selected after an ethnobotanic survey in the region of the Pool (Congo Brazzaville): Leonotis nepetaefolia (Lamiaceae), Manotes pruinosa (Connaraceae), Spilanthes uliginosa (Asteraceae), Hymenocardia ulmoides (Euphorbiaceae), Celosia trigyna (Amaranthaceae), Cogniauxia podolaena (Cucurbitaceae), Brillantaisia patula (Acanthaceae), Urena lobata (Malvaceae), Mitracarpus scaber (Rubiaceae), Triumfetta rhomboidea (Tiliaceae). The cytotoxicity of all the extracts was tested on KB (Human epidermoid Carcinoma) & Vero (African green monkey kidney) cell lines with Taxotere as positive control.

   • Selon Auteur (2015)

     Extrait The leaves of Urena lobata growing along the sides of busy roads of Oluku, Agbor & Sapele in Benin City were studied vis-à-vis those growing in forest areas of Ebvomodu, Eyaen & Ebvoneka villages in the outskirt of Benin City for the activity of air pollution. The epidermal cell walls of leaves of the polluted and non-polluted populations of this species were sinuous in both leaf surfaces and comprised of diacytic stomata.

   • Selon Oladele G (2010)

     Extrait The rats treated with Hyptis suaveolens also showed a significant decrease (p<0.05) in headless tail which may be of significant effect to their fertility, while the rats treated with U lobata extract showed a significant increase (p<0.05) in headless tail sperm cell abnormality,. The plants Hyptis suaveolens, Cleome viscosa & Urena lobata are herbs commonly found growing in pasture & also used as medicinal plant in Nigeria.

3. 3

   Hyperalgie, douleur

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Islam MT (2012)

     Extrait lobata produced significant (p<0.05) pain relieving activity (number of writhing 32) at 500 mg/kg body weight as compared to standard diclofenac-Na. From this view point two Bangladeshi plants, Uraria lagopodies DC & Urena lobata have been evaluated for their possible pharmacological activities.

   • Selon Islam H (2015)

     Extrait In oral glucose tolerance tests with methanolic extract of Urena lobata leaves (MEUL), the extract significantly & dose-dependently reduced blood glucose concentrations in glucose-loaded mice. In analgesic activity tests with acetic acid induced pain model mice, the extract at the afore-mentioned four doses, significantly and dose-dependently reduced acetic acid induced abdominal constrictions in mice by 18.5, 22.2, 40.7, & 63.0% versus the 48.1 & 63.0% reductions obtained with a standard analgesic drug, aspirin, administered respectively, at doses of 200 & 400 mg per kg.

   • Selon MAKANBILA MC (2011)

     Extrait Thirty-three extracts were obtained in 3 different solvents (Water, Ethanol, DCM) from these ten plants selected after an ethnobotanic survey in the region of the Pool (Congo Brazzaville): Leonotis nepetaefolia (Lamiaceae), Manotes pruinosa (Connaraceae), Spilanthes uliginosa (Asteraceae), Hymenocardia ulmoides (Euphorbiaceae), Celosia trigyna (Amaranthaceae), Cogniauxia podolaena (Cucurbitaceae), Brillantaisia patula (Acanthaceae), Urena lobata (Malvaceae), Mitracarpus scaber (Rubiaceae), Triumfetta rhomboidea (Tiliaceae). The aim of this study was to assess ten plants from the Congolese Pharmacopeia for their analgesic activity as well as their cytotoxicity, in order to validate their traditional use.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.