Vitis vinifera (Rézen) : vertus médicinales en extraction alcoolique

Vitis vinifera (Rézen, raisin) — famille Vitacées.

Synonymes scientifiques : ---.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 17 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 56 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Semence. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon NERMIEN Z (2016)

     Extrait This study aim to determine the protective effect of Grape seeds (Vitis vinifera) ethanolic extract against streptozotocin-induced diabetic rats. Also, it can be speculated that Grape seed (Vitis vinifera) ethanolic extract has a hypoglycemic effect possibly related to the phytochemical compounds of Vitis vinifera plant seeds include Gallic acids, Catechin, Ρ-hydroxy Benzoic acid, Vanillin, Ferulic acid, Ρ-Coumaric acid, Euganol , as well as, 5,7- Dihydroxy 4-methoxy isoflavone which can optimize sugar uptake in the liver.

   • Selon Margină D (2015)

     Extrait The results of the present study may be translated into clinical practice & demonstrate that C longa extracts may be effective in both the prevention of diabetes mellitus & in attenuating the development of complications associated with the disease. In the present study, we aimed to obtain & characterize certain extracts from Vitis vinifera L., Aesculus hippocastanum L.

   • Selon GIRIBABU N (2015)

     Extrait Methods : VV seed ethanolic extract (250 & 500 mg/kg/day) or Glibenclamide (600 μg/kg/day) was administered to streptozotocin-induced male diabetic rats for 28 consécutive days. vinifera seeds on carbohydrate metabolizing enzymes and other enzymes of the liver in diabetes is currently unknown.

   • Selon KORKMAZ N (2025)

     Extrait Objective: In this study, the protective potential of grape (Vitis vinifera L.) seed extract (GSE) against the toxic effects of cadmium (Cd) on growth hormone, stress hormones, & thyroid hormones in common carp (Cyprinus carpio L.) was investigated for the first time. Results: Cadmium exposure caused significant hormonal disruptions in common carp, including reductions in growth hormone, insulin-like growth factor 1, thyroid-stimulating hormone, & triiodothyronine levels, along with elevations in cortisol & thyroxine levels during both acute & subchronic exposure periods (P < 0.05).

   • Selon Zeytünlüoğlu A (2015)

     Extrait Results: Among the tested plants Vitis vinifera L., Artemisia dracunculus L., Prunus laurocerasus L., Rubus caesius L. Dipeptidyl peptidase IV (DPP IV) is a serine amino (exo) peptidase which regulates various processes most notably plasma glucose homeostasis by cleaving incretin peptide hormones as glucagon-like peptide-1 (GLP-1) & glucose-dependent insulin releasing polypeptide (GIP).

2. 2

   Cirrhose, hépatite, stéatose hépatique

   Partie usitée : Feuille. Profil pharmacologique documenté : Legalon-like, Silymarine-like. Association synergique mentionnée : Centella asiatica-plante entière.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Munakarmi S (2023)

     Extrait Liver injury can be acute or chronic, resulting from a variety of factors, including viral hepatitis, drug overdose, idiosyncratic drug reaction, or toxins, while the progression of pathogenesis in the liver rises due to the involvement of numerous cytokines & growth factor mediators. (VE) & Centella asiatica (CE) are well-known medicinal plants that possess anti-inflammatory & antioxidant properties.

   • Selon ORHAN DD (2007)

     Extrait The hepatoprotective effect of ethanolic extract and its four different fractions (CHCl3, EtOAc, n-BuOH, & remaining water fraction) of Vitis vinifera L. The ethanolic extract was fractionated through successive solvent–solvent extractions & the n-BuOH fraction in 83 mg/kg dose possessed remarkable antioxidant and hepatoprotective activities.

   • Selon SHARMA SKR (2012)

     Extrait The ethanolic extract of the root of Vitis vinifera (Vitaceae) was evaluated for hepatoprotective activity in rats with liver damage induced by carbon tetrachloride. These biochemical observations were supplemented by histopathological examination of liver sections.

   • Selon NERMIEN Z (2016)

     Extrait Also, it can be speculated that Grape seed (Vitis vinifera) ethanolic extract has a hypoglycemic effect possibly related to the phytochemical compounds of Vitis vinifera plant seeds include Gallic acids, Catechin, Ρ-hydroxy Benzoic acid, Vanillin, Ferulic acid, Ρ-Coumaric acid, Euganol , as well as, 5,7- Dihydroxy 4-methoxy isoflavone which can optimize sugar uptake in the liver. This study aim to determine the protective effect of Grape seeds (Vitis vinifera) ethanolic extract against streptozotocin-induced diabetic rats.

   • Selon GIRIBABU N (2015)

     Extrait vinifera seed ethanolic extract was able to prevent the decrease in ICDH, SDH, MDH, and G-6-PDH & the increase in LDH activity levels in liver homogenates. vinifera seeds on carbohydrate metabolizing enzymes and other enzymes of the liver in diabetes is currently unknown.

3. 3

   Cancer: traitement adjuvant du carcinome mammaire

   Partie usitée : Semence. Association synergique mentionnée : Ixora coccinea-fleur, Piper longum-racine.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Balea SS (2020)

     Extrait Because grape pomace is a rich source of antioxidant compounds, the purpose of the study was to evaluate the antioxidant, anti-inflammatory, & antiproliferative effects of fresh & fermented grape pomace extracts of two Vitis vinifera L. Thirdly, the antiproliferative properties were evaluated on human lung carcinoma (A549), human breast adenocarcinoma (MDA-MB-231), murine melanoma (B164A5), & keratinocyte (HaCat) cell lines.

   • Selon PERIYANAYAGAM P (2013)

     Extrait To prescreen the in vivo antimitotic & antiproliferative activity of the leaves of Vitis vinifera. vinifera (Vitaceae), Common Grape Vine was selected for phytochemical & pharmacological screening of antimitotic & antiproliferative activity.

   • Selon Balea ŞS (2020)

     Extrait Thirdly, the antiproliferative properties were evaluated on human lung carcinoma (A549), human breast adenocarcinoma (MDA-MB-231), murine melanoma (B164A5), & keratinocyte (HaCat) cell lines. Because grape pomace is a rich source of antioxidant compounds, the purpose of the study was to evaluate the antioxidant, anti-inflammatory, & antiproliferative effects of fresh & fermented grape pomace extracts of two VV varieties Fetească neagră & Pinot noir cultivated in Romania.

   • Selon Nelson S.S (2019)

     Extrait The anticancer potentials of the seed extracts of edible fruits pomegranate (Punica granatum L.), guava (Psidium guajava L.) & grapes (Vitis vinifera L.) were evaluated. Among the selected edible fruit seeds & their different organic solvent extracts, the ethyl acetate extract of P granatum possessed a higher inhibitory effect against lung cancer cell line, compared to other solvent extracts of P guajava & V vinifera fruit seeds, & the IC 50 value was 51.25 ± 1.25 μg/ml, 60.21 ± 1.35 μg/ml & 61.21±1.45μg/ml, respectively.

   • Selon Urolagin DK (2018)

     Extrait Here, we investigated the anti-cancer effects of 3 drug extracts-Vitis vinifera-Grape seeds (GSE), Ixora coccinea flower & Piper longum root extract against breast cancer treatment. The percentage inhibition of V vinifera (10–320 µg/ml), I coccinea (10–320 µg/ml) & P longum (10–320 µg/ml) treatment of cells resulted in 10–90%, 6-53% & 14-90% growth inhibition respectively.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.