Wedelia sphagneticola (Brenbal) : vertus médicinales en extraction alcoolique

Wedelia sphagneticola (Brenbal, boyo-tôti, Flè, solèy, Brimbale, Boyau-à-tortue, Fleur soleil) — famille Asteracées.

Synonymes scientifiques : Acmella spilanthoides Cass., Buphthalmum procumbens Desf., Wedelia trilobata –(L)-Hitchcrenata.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 11 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 78 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Buddhhakala N (2020)

     Extrait The antidiabetic activity was examined by orally administering ST extract of 250 mg/kg body weight to streptozotocin-induced diabetic rats on a daily basis for eight weeks; & the body weight, blood glucose, serum insulin, & lipid profiles were determined. trilobata, METHODS: This research investigates the toxicity and antidiabetic activity of Sphagneticola trilobata flower ethanolic extract in rats.

   • Selon Kade IJ (2010)

     Extrait Kade IJ et al, Aqueous extracts of Sphagneticola trilobata attenuates streptozotocin-induced hyperglycaemia in rat models by modulating oxidative stress parameters Biol & Med, 2010; 2(3):1-13,.

   • Selon Schmitz P (s.d.)

     Extrait Cissus verticillata & Sphagneticola trilobata have been used in Brazilian folk medicine for Diabetes Mellitus treatment, although their pharmacological & toxicological profile has not been clearly established.

   • Selon Mizokami SS (2012)

     Extrait Furthermore, the analgesic effect of 1 was inhibited by l-NAME, ODQ, KT5823, & glibenclamide treatment, demonstrating that such activity also depends on activation of the NO–cyclic GMP–protein kinase G–ATP-sensitive potassium channel signaling pathway, respectively. Kaurenoic acid [ent-kaur-16-en-19-oic acid (1)] is a diterpene present in several plants including Sphagneticola trilobata.

   • Selon Chethan J (2014)

     Extrait Artimisia vulgaris, Eclipta alba, Glossocardia bosvallea, Wedelia chinensis & Wedelia trilobata showed inhibition of α-amylase and α- glucosidase enzymes that are responsible for the breakdown of oligosaccharides into monosaccharides. Antidiabetic & Antihypertensive activity of 10 ethnobotanically known plants of Asteraceae family was investigated using in vitro glucose diffusion, α-amylase, α-glucosidase & Angiotensin I converting enzyme (ACE) inhibition methods.

2. 2

   Inflammation : douleur inflammatoire

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Masuma R (2021)

     Extrait The present study was investigated to evaluate the analgesic, anti-inflammatory & antipyretic effect of Wedelia trilobata. Treatment with WT at both the doses reduced pyrexia very highly significantly (p<0.001) in yeast induced antipyretic test.Results from the studies suggested that the WT extract showed potent analgesic, anti-inflammatory & antipyretic effects in various animal models.

   • Selon Fucina G (2016)

     Extrait The aerial parts of Sphagneticola trilobata (L.) Pruski (Asteraceae) are popularly used to treat topical inflammation, but have not been fully investigated. The extent of ear edema induced by applying 20 μL of croton oil (2.5%), arachidonic acid (AA; 2 mg/ear) & decanoylphorbol-13-acetate (TPA; 2.5 mg/ear) in mice was used to evaluate the biological activity of the semisolids, which were applied 30 min before the phlogistic agents.

   • Selon Meena AK (2011)

     Extrait It is an interesting source of potential bioactive molecules, as iridoids compounds, flavonoids, diterpenoids derivatives, phytosteroids, with antioxidant, anti-inflammatory, antimicrobial, Hepatoprotective activity, analgesic & antihistamine ,Anti-implantation, antiasthmatic activities & anticancer activity. This work reviews the pharmacological evidence of extracts of plants from the genus Wedelia, giving an overview of the most studied biological effects & the known phytochemical composition.

   • Selon Lang K (2017)

     Extrait the aim of this work was to investigate the thermostability of herbal derivatives of the aerial parts of Sphagneticola trilobata, a reputed medicinal plant; to biomonitor its oral anti-hyperalgesic effect; & to elucidate the degradation pathways of the major components by UHPLC-ESI-QTOF-MS. These results provide a relevant guide for the extraction process of ST, aimed at preserving the antinociceptive effect.

   • Selon Sureshkumar S (2007)

     Extrait Wedelia trilobata (EEWT), Wedelia biflora (EEWB) & Eclipta alba (EEEA) was evaluated by acetic acid induced writhing method & hot plate assay to assess analgesic activity in mice. The results reflects that analgesic effects & therapeutic efficacy of the extract on animal models which are comparable with those of standard drugs such as Aspirin & Morphine,.

3. 3

   Cancer : traitement adjuvant de la leucémie myéloïde et du sarcome

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Murali M (2022)

     Extrait In addition, the cytotoxic ability of the StZnO-NPs against the HT-29 colon cancer cells & human erythrocytes revealed that the particles were cytotoxic towards HT-29 cells, while insignificant effect against the human erythrocytes. the same the present study was designed to biosynthesize zinc oxide nanoparticles (ZnO-NPs) from the aqueous leaf extract (ALE) of medicinally important plant Sphagneticola trilobata L.

   • Selon Mardina V (2020)

     Extrait The antioxidant and anticancer activities were assessed by 1,1-diphenyl-2-picrylhydrazyl free radical scavenging and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay methods, respectively. In this study, the antioxidant & anticancer properties of the ethyl acetate extract from S.

   • Selon Surbaki Juanda B (2021)

     Extrait The use of plant extracts as a preventive or curative in cases of tumors/cancer has been reported, however there is no reports about the in vivo study for Sphagneticola trilobata plant. This study aims to examine the anticancer effect of the methanol extract of ST leaves using histology observation on Wistar rat (Rattus novergicus) kidney which was induced by 7,12 dimethylbenz [α] anthracene (DMBA).

   • Selon Auteur (2012)

     Extrait Since WT 4-4 could significantly inhibit the growth of S-180 cell line, in vivo antitumor assay using Sarcoma 180 tumor-bearing BALB/c mice was also carried out. After screening the antitumor activity of water extracts of four Compositae species, Wedelia thlobata was chosen for detailed investigation in this project.

   • Selon Zhang B (2023)

     Extrait All eudesmanolides were evaluated for their anti-proliferative activities against four human tumor cell lines (HepG2, HeLa, SGC-7901, & MCF-7). Twenty-six eudesmanolides including six undescribed compounds were isolated from the flowers of Sphagneticola trilobata (L.) Pruski.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.