Averrhoa bilimbi (Bilenmbi) : vertus médicinales en extraction alcoolique

Averrhoa bilimbi (Bilenmbi, Kornichon, Bilimbi, cornichon, gherkin) — famille Oxalidacées.

Synonymes scientifiques : Averrhoa obtusangulata-Stokes, A. obtusangula-Stokes.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 20 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 66 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Fruit. Profil pharmacologique documenté : Glibenclamide-like. Association synergique mentionnée : Catharanthus roseus-feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon ALIPIN K (2019)

     Extrait Diabetes mellitus (DM) is a metabolic disorder characterized by high blood glucose levels or hyperglycemia due to deficiency or ineffectiveness of insulin. This study aims to determine the effectiveness & optimum dosage combination CX rhizomes & AB fruit extract as anti-diabetic herbs in decreasing blood glucose levels, improve pancreas histopathology & the liver structure repair of diabetic male Wistar rats induced by streptozotocin.

   • Selon Sutrisna EM (2015)

     Extrait roseus G doses 40 :80 & 80 :40 mg/200 gBW had the effect of lowering Blood glucose Levels in 7 days, but couldn’t prevent renal damage by induction of alloxan. roseus G) leaves extract in lowering blood glucose levels.

   • Selon Wardani BPN (2021)

     Extrait Hyperglycemia is a condition of excessive blood glucose in blood plasma caused by damage to the pancreatic beta-cell structure that causes impaired insulin secretion. The conclusion of this study was MC & AB ethanol extract with a treatment of 40 mg.kg-1 BW can suppress IL-1b pro-inflammatory cytokines in hyperglycemic mice models, but has not been able to reduce the expression of IL-6 pro-inflammatory cytokines.

   • Selon Pushparaj P (2001)

     Extrait In the present study, we have examined the possible mechanism of the hypoglycemic action of the semi-purified fractions of an ethanolic extract of Averrhoa bilimbi Linn (Oxalidaceae) leaves (ABe) in streptozotocin-diabetic male Sprague-Dawley (SD) rats. Fractions AF, BuF & the reference drug Metformin (500 mg/kg body weight), produced significant blood glucose-lowering effect in the diabetic rats when compared to the vehicle (distilled water).

   • Selon Daud N (2013)

     Extrait An ethanolic extract of leaves & fruits of Averrhoa bilimbi (250 mg/kg) was orally administered to normal & diabetic male rats for 14 consecutive days. Hypercoagulation, which is often associated with diabetes mellitus may lead to several health problems such as thrombosis, stroke & heart attack.

2. 2

   Cancer : chemoprevention : hépatocarcinome

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Pushparaj P (2001)

     Extrait In the present study, we have examined the possible mechanism of the hypoglycemic action of the semi-purified fractions of an ethanolic extract of Averrhoa bilimbi Linn (Oxalidaceae) leaves (ABe) in streptozotocin-diabetic male Sprague-Dawley (SD) rats. Hepatic glucose-6-phosphatase activity was significantly lower (P<0.05) in AF- & metformin-treated groups, but not in BuF-treated groups, compared to that in vehicle-treated group.

   • Selon Ali R (2013)

     Extrait bilimbi possesses effective cytotoxic properties & hence can be à potential source for the isolation of active principle(s) for cancer therapy. The crude methanolic extract of Averrhoa bilimbi Linn.

   • Selon Nair MS (2016)

     Extrait The fruit & leaf extracts of Averrhoa bilimbi were analyzed for the presence of phytochemicals, flavonoid content & in vitro cytotoxic potential. The methanolic fruit extract exhibited significant cytotoxic potential against MCF-7 human breast cancer cell lines with an IC50 value of 154.9 μg/ ml whereas an IC50 value of 668 μg/ml observed for ethanolic leaf extract.

   • Selon Yan SW (2017)

     Extrait This study investigated the growth inhibitory & antiproliferative effect as well as the underlying cell death pathway induced by bilimbi (Averrhoa bilimbi) ethanolic extract on human cervical cancer cell line, HeLa. Collectively, this study suggests bilimbi ethanolic extract as a potential anticancer agent capable of inducing growth inhibitory effect & apoptosis on cervical cancer cell line.

   • Selon Singh R (2014)

     Extrait This study suggests the prophylactic role of A carambola against hepatocellular carcinoma in mice ; therefore, it could be employed for the further screening as a good chemopreventive natural supplement against cancer.Liver cancer remains one of the severe lethal malignancies worldwide and hepatocellular carcinoma (HCC) is the most common form. in corn oil thrice a week for 24 weeks) liver cancer in Swiss albino mice.

3. 3

   Infection bacterienne : Staphylococcus aureus, Escherichia coli

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Widhianto EK (2017)

     Extrait The bacteria used to test are Gram + Staphylococcus aureus & Gram-Escherichia coli, both of which are pathogenic bacteria in humans. Averrhoa bilimbi L, or in Indonesian named belimbing wuluh has been widely used by the Community as a complement to cuisine.

   • Selon Mannan A (2020)

     Extrait PE & EA fractions exhibited good antimicrobial activity with the zone of inhibition against Bacillus cereus (11 mm & 14 mm) & Escherichia coli (7 mm & 9 mm). bilimbi) fruit has been subjected in this research to find out a possible source of bioactive compounds against antimicrobial & cytotoxic activity.

   • Selon Gunawan C (2013)

     Extrait This included Squalene (1); 3-(6,10,14-trimethylpentadecan-2-yl)furan-2(5H)-one (2 A new compound); 2,3-bis(2,6,10-trimethylundeca-1,5,9-trienyl)oxirane (3 A new compound) with negative activity towards a-glucosidase inhibitory assay, Kirby-Bauer antimicrobial assay & DPPH radical scavenging assay]; phytol (4); 3,4-Dihydroxyhexanedioic acid (5) which was isolated for the first time from a natural source; malonic acid (6); & 4,5-Dihydroxy-2-methylenehydroxybenzaldehyde (7). bilimbi leaves were obtained by exhaustive extraction with methanol at ambient temperature.

   • Selon Jais AMM (2007)

     Extrait Jais AMM et al, In vitro antibacterial activity of Averrhoa bilimbi L.

   • Selon Aziz A (2014)

     Extrait The study was carried out to assess the antibacterial & cytotoxic activities of extracts from leaf parts of the plant, Averrhoa bilimbi. Water extract exhibited more potent antimicrobial activity by inhibiting wide range of gram positive & gram negative bacteria in comparison to ethanolic & methanolic extract of leaves of A.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.