Calotropis procera (Bwa-laswa) : vertus médicinales en extraction alcoolique

Calotropis procera (Bwa-laswa, Bois-à-soie, Silkwood) — famille Asclépiadacées.

Synonymes scientifiques : Asclepias procera Aiton, Calotropis gigantea-Maycock.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 20 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 122 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Hépatite, cirrhose, stéatose hépatique

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Setty RC (2007)

     Extrait Hydroethanolic extract (70%) of Calotropis procera flowers was prepared and tested for its hepatoprotective effect against paracetamol-induced hepatitis in rats. procera flowers (200 mg/kg and 400 mg/kg) has brought back the altered levels of biochemical markers to the near normal levels in the dose dependent manner.

   • Selon Parihar G (2011)

     Extrait The ethanolic extract of root bark of Calotropis procera R.br. The extract of Calotropis procera (CPE) exhibited significant anti-inflammatory effect at the dose 100 and 200 mg/kg.

   • Selon Choedon T (2006)

     Extrait To evaluate the anticancer property of the dried latex (DL) of Calotropis procera, a tropical medicinal plant, in the X15-myc transgenic mouse model of hepatocellular carcinoma & to elucidate its mechanism of action in cell culture. METHODS: The young transgenic mice were orally fed with the aqueous suspension of DL (400 mg/kg for 5 d/wk) for 15 wk and their liver was examined for histopathological changes at 20 wk.

   • Selon Murshed M (2023)

     Extrait The research aimed to assess the efficacy of Calotropis procure leaf extracts on the inhibition of Eimeria stiedae oocysts & to determine the optimal dosage for suppressing the parasite's infective phase. Hepatic coccidiosis is an infectious & mortal disease that causes global economic losses in rabbits.

   • Selon Basu A (1992)

     Extrait Basu A et al, Hepatoprotective effects of Calotropis procera root extract on experimental liver damage in animals.

2. 2

   Diabète mellitus de type II

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Kazeem MI (2016)

     Extrait It can be concluded from this study that the C procera extracts could serve as source of antidiabetic agents which may act through the inhibition of carbohydrate hydrolyzing enzymes, α-amylase and α-glucosidase. This study was aimed at evaluating the α-amylase and α-glucosidase inhibitory potential of C procera leaf, as well as its possible mode of inhibiting these enzymes.

   • Selon Roy S (2005)

     Extrait In the present study, dry latex (DL) of Calotropis procera possessing potent anti-inflammatory activity was evaluated for its antioxidant & anti-hyperglycemic effects against alloxan-induced diabetes in rats. DL also produced an increase in the hepatic levels of the endogenous antioxidants, namely superoxide dismutase (SOD), catalase & glutathione, while it brought down the levels of thiobarbituric acid-reactive substances (TBARS) in alloxan-induced diabetic rats.

   • Selon Auteur (2022)

     Extrait Imosemi I, EVALUATION OF THE TOXICITY, MEDICINAL USE & PHARMACOLOGICAL ACTIONS OF CALOTROPIS PROCERA, Eur J of Pharmaceut & med Res, 3(9):28-36, 2022-A bstract: Calotropis procera also known as the giant milk weed is one of the flowering plants commonly found in the tropic’s world over. procera possesses anti-inflammatory, antibacterial, antipyretic, antidiabetic, anticancer & antioxidant properties.

   • Selon Neto MCL (2013)

     Extrait Neto MCL et al, Evaluation of antihyperglycaemic activity of Calotropis procera leaves extract on streptozotocin-induced diabetes in Wistar rats.

3. 3

   Cancer traitement adjuvant du carcinome : colorectal

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon BHAGAT M (2010)

     Extrait In vitro assay for cytotoxic activity of the stem-leaves of Calotropis procera was carried out against human cancer cell lines at the concentration of 10, 30 and 100g/ml. Results revealed that the extracts of the plant possessed in vitro anticancer potential against HCT-15 (colon) cancer cell line at different concentrations.

   • Selon Choedon T (2006)

     Extrait To evaluate the anticancer property of the dried latex (DL) of Calotropis procera, a tropical medicinal plant, in the X15-myc transgenic mouse model of hepatocellular carcinoma & to elucidate its mechanism of action in cell culture. procera has the potential for anticancer therapy due to its differentiable targets and non-interference with regular pathway of apoptosis.

   • Selon Arul B (2004)

     Extrait The antitumor activity of the ethanolic extract of Calotropis procera R. After 14 d of inoculation with DAL cells, ECP is able to reverse the changes in the haematological parameters, protein and packed cellular volume consequent to tumor inoculation.

   • Selon Auteur (2022)

     Extrait Imosemi I, EVALUATION OF THE TOXICITY, MEDICINAL USE & PHARMACOLOGICAL ACTIONS OF CALOTROPIS PROCERA, Eur J of Pharmaceut & med Res, 3(9):28-36, 2022-A bstract: Calotropis procera also known as the giant milk weed is one of the flowering plants commonly found in the tropic’s world over. procera possesses anti-inflammatory, antibacterial, antipyretic, antidiabetic, anticancer & antioxidant properties.

   • Selon Van Quaquebeke E (2005)

     Extrait Identification of a novel cardenolide (2-oxovoruscharin) from Calotropis procera & the hémi synthesis of novel derivatives displaying potent in vitro antitumor activities and high in vivo tolerance: Structure-activity relationship analyses.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.