Conyza bonariensis (Zèb-kodenn) : vertus médicinales en extraction alcoolique

Conyza bonariensis (Zèb-kodenn, herbe-à-coq d’Inde) — famille Asteracées.

Synonymes scientifiques : Erigeron bonariensis-L, Leptilon bonariense-(L)-Small..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 6 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 35 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Akhtar MF (2021)

     Extrait The plant extract (250 & 500mg/kg/day) was explored for its anti-hyperglycemic effect for 14 days in normoglycemic & alloxan-induced diabetic rats using the oral glucose tolerance test (OGTT). To evaluate the anti-diabetic potential of aqueous methanolic extract of Conyza bonariensis amongst the Wistar rats.

   • Selon MUSTAFA I (2024)

     Extrait Total oxidant status (TOS) and the serum glucose levels of the streptozotocin-treated rats were reduced significantly (P ⩽ .05) in Conyza bonariensis treated group. This study was conducted to assess the possible antidiabetic potential of Conyza bonariensis by employing in vitro as well as in vivo assessments.

   • Selon Saleem M (2021)

     Extrait The plant extract (250 a&500mg/kg/day) was explored for its anti-hyperglycemic effect for 14 days in normoglycemic & alloxan-induced diabetic rats using the oral glucose tolerance test (OGTT). To evaluate the anti-diabetic potential of aqueous methanolic extract of Conyza bonariensis amongst the Wistar rats.

   • Selon AL-KAZMAN BSM (2025)

     Extrait Conyza bonariensis (CB), a traditional medicinal plant, has demonstrated antioxidant, anti-inflammatory, and hepatoprotective properties, making it a promising candidate for NAFLD therapy. Non-alcoholic fatty liver disease (NAFLD) is a rising global health concern closely linked with obesity, insulin resistance, and metabolic syndrome.

2. 2

   Cancer : traitement adjuvant du carcinome hépatique et mammaire

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Saleem M (2014)

     Extrait The hepatoprotective activity of Conyza bonariensis ethanol extract was studied against paracetamol induced hepatotoxicity in mice. The results showed that an extract of C.B (250 mg/kg & 500 mg/kg) produced (p<0.05) decline in paracetamol induced liver marker enzymes & total bilirubin, but its 750 mg/kg showed remarkable decline in ALT, AST, ALP & TB levels, compared to the reference levels of silymarin & results were supported by histopathology of liver section.

   • Selon AL-KAZMAN BSM (2025)

     Extrait In vivo, extract-treated groups showed significant improvement in liver function tests, lipid profiles, and oxidative stress markers (p < 0.05), with the highest dose group (750 mg/kg) displaying histologically reduced hepatic steatosis and inflammation. Conyza bonariensis (CB), a traditional medicinal plant, has demonstrated antioxidant, anti-inflammatory, and hepatoprotective properties, making it a promising candidate for NAFLD therapy.

   • Selon BATOOL S (2025)

     Extrait The leaf extract, showing the most promising anticancer activity, was further analyzed against liver cancer cells, yielding an IC50 value of 1.72 μg mL−1. Conyza bonariensis, commonly named “dhania booti” in the context of Pakistan, is a species classified within the Asteraceae family & exhibits a multitude of biomedicinal applications.

   • Selon LAHNGONG M (2025)

     Extrait Conyza bonariensis (L.) Cronquist) is a medicinal plant with traditional use in Cameroonian folk medicine & other parts of Africa for the management of ailments, including malaria. Additionally, cytotoxicity was assessed on the MDA-MB-231 breast cancer cell line, while acute & sub-chronic toxicity were evaluated using albino mice.

   • Selon Akhtar MF (2021)

     Extrait To evaluate the anti-diabetic potential of aqueous methanolic extract of Conyza bonariensis amongst the Wistar rats. The plant extract revamped the pancreatic islets of Langerhans & abridged alloxan-induced degenerative changes in the liver.

3. 3

   Infection fongique : Candida albicans, C. parapsilosis, Malassezia furfur, M. globosa, M Sympodialis, Microsporum canis, Trichophyton rubrum, T mentagrophytes

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Mussin je (2017)

     Extrait parapsilosis), 17 dermatophytes (6 Trichophyton rubrum, 6 Trichophyton mentagrophytes, 5 Microsporum canis) & 6 Staphylococcus aureus. Conclusions: Results allow to conclude that the CB tincture displays antibacterial activity against Staphylococcus aureus & antifungal activity against the main fungi causing superficial infections, such as dermatophytes, Candida & Malassezia.

   • Selon GIRMA Y (2021)

     Extrait Antimicrobial activity of the extracts was evaluated against pathogenic fungi causing superficial infection (Candida albicans, Malassezia globosa, & Malassezia furfur). In this study, crude extracts from leaves of Conyza bonariensis were prepared using methanol, ethyl acetate, hexane, & chloroform.

   • Selon ARAUJO L (2013)

     Extrait Additionally, the essential oil presented a significant bactericidal effect against Bacillus cereus, while a moderate activity was observed against Staphylococcus epidermidis & Candida albicans. The essential oil from aerial parts of Conyza bonariensis (L) Cronquist collected in Mérida was obtained by hydrodistillation & analysed by GC/MS.

   • Selon MPENDA FN (2024)

     Extrait Methods: Initial experimental activities involved preparation of crude extracts & EO, which were then, tested for antimicrobial activity against selected test organisms (Staphylococcus aureus (ATCC29213), Bacillus subtilis (ATCC6051), Escherichia coli (ATCC8736), Salmonella typhi (ATCC6539), & Candida albicans (DSM1665)) by using the disc diffusion method. albicans, where the MIC was 50 mg/mL > MIC > 25 mg/mL.

   • Selon NSINDAGI SP (2023)

     Extrait Then crude extracts were tested against selected microorganisms: Two Gram-positive bacteria, Staphylococcus aureus & Bacillus subtilis; Two Gram-negative bacteria, Escherichia coli & Salmonella typhi, & a yeast Candida albicans.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.