Cucumis sativus (Konkonb) : vertus médicinales en extraction alcoolique

Cucumis sativus (Konkonb, Concombre, Cucumber) — famille Cucurbitacées.

Synonymes scientifiques : Cucumis erinaceus-hort., Cucumis grassulariformis-hort..

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 14 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 37 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome hépatique

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Muruganantham N (2016)

     Extrait The compound isolated from ethyl acetate fraction of Cucumis sativus flowers was tested for its anti-cancer activity against liver cancer HePG2 cell line by MTT assay. This Present study explains a very superior anticancer action against liver cancer.

   • Selon Heidari H (2012)

     Extrait Conclusions: Our results showed that aqueous extract of C sativus acts as a hepatoprotective & antioxidant agent against CHP-induced hepatotoxicity suggesting that antioxidants & radical scavenging components of C sativus fruit extract can easily cross the cell membrane & cope with the intracellular ROS formation. Heidari H et al, Hepatoprotective activity of Cucumis sativus against cumene hydroperoxide induced-oxidative stress.

   • Selon Muruganantham N (2016)

     Extrait Fresh flowers of Cucumis sativus were extracted & evaluated for antioxidant activities by 2,2-Diphenyl 1-picryl hydrazyl solution (DPPH), 2,2'-azino-bis (3-ethylbenzthiazoline-6-sul- phenic acid (ABTS) assay & anti-inflammatory activities by human blood cell (HRBC) membrane stabilization method & Inhibition of albumin denaturation method. The results obtained showed that the compound isolated from ethyl acetate fractions of C sativus flowers can be considered as good sources of antioxidants, anti-inflammatory & can be incorporated into the drug formulations.

   • Selon Mallik J (2012)

     Extrait The present study was aimed to investigate phytochemical screening & to evaluate reducing power, cytotoxicity & antifungal activities of the ethanol extracts of peels of Cucumis sativus Linn (Cucurbitaceae). The qualitative phytochemical tests showed the presence of alkaloids, glycosides, saponins, flavonoids, steroids & tannins in the ethanol extract of C sativus while gums and reducing sugar were absent in the ethanol extract 3.

2. 2

   Diabète mellitus de type II

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Kathyayini T (2009)

     Extrait The oral administration of 200 & 400 mg/kg body weight of ethanol extracts of powder fruit of C sativus exhibited significant antidiabetic effects in streptozotocin induced rats as compared to standard drug. In order to evaluate the antidiabetic activity of powder fruit of Cucumis sativus.

   • Selon Heidari H (2012)

     Extrait 7(5): S936-9, 2012.-Aims: The fruit of Cucumis sativus a plant that has long been used in oriental medicine for its anti-inflammatory, antidiabetic & abortifacient effects. Results: In the present study, the antioxidative potential of Cucumis sativus was evaluated in isolated rat hepatocytes and we tried to figure out whether Cucumis sativus could protect hepatocytes against cumene hydroperoxide (CHP) induced-cytotoxicity and ROS formation.

   • Selon Saidu AN (2014)

     Extrait Saidu AN et al, Phytochemical screening & hypoglycemic effect of methanolic fruit pulp extract of Cucumis sativus in alloxan induced diabetic rats.

   • Selon Qamar M (2021)

     Extrait It is known to anticipate antioxidant, anti-inflammatory, anticancer, anti-diabetic, anti-bacterial, antifungal, activities, & radioprotective activities. cumini have been used to cure renal issues, indigestion, diabetes, dysentery, & employed in folk medicine to treat inflammations.

3. 3

   Infection bactérienne : Bacillus Cereus, Bacillus subtilis, Streptococcus faecalis, three gram negative bacteria, viz. Pseudomonas aeruginosa, Klebsiella aerogenes, Proteus vulgaris

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Gopalakrishna BS (2014)

     Extrait Ethanolic extract of the fruits of Cucumis sativus had a minimum inhibitory concentration (MIC) of 200 µg/ml against three-gram positive bacteria, viz., Bacillus Cereus, Bacillus subtilis, Streptococcus faecalis, three-gram negative bacteria, viz., Pseudomonas aeruginosa, Klebsiella aerogenes, Proteus vulgaris & the two fungi, Candida albicans, Aspergillus flavens. Materials & methods: Antimicrobial activities of petroleum ether (40-60ºC), benzene, chloroform, ethanol & water extracts of the fruits of C sativus have been investigated against both bacteria & fungi using the disc diffusion method.

   • Selon Mallik J (2012)

     Extrait The present study was aimed to investigate phytochemical screening & to evaluate reducing power, cytotoxicity & antifungal activities of the ethanol extracts of peels of Cucumis sativus Linn (Cucurbitaceae). The qualitative phytochemical tests showed the presence of alkaloids, glycosides, saponins, flavonoids, steroids & tannins in the ethanol extract of C sativus while gums and reducing sugar were absent in the ethanol extract 3.

   • Selon Qamar M (2021)

     Extrait It is known to anticipate antioxidant, anti-inflammatory, anticancer, anti-diabetic, anti-bacterial, antifungal, activities, & radioprotective activities.

   • Selon Janatunaim RZ (2014)

     Extrait sativus fruit contain of glycosides, steroids, flavonoids, carbohydrates, terpenoids & tannins. Controls used in this research is a mixture of water with DMSO as much as three replicates.

   • Selon Muruganantham N (2016)

     Extrait Fresh flowers of Cucumis sativus were extracted & evaluated for antioxidant activities by 2,2-Diphenyl 1-picryl hydrazyl solution (DPPH), 2,2'-azino-bis (3-ethylbenzthiazoline-6-sul- phenic acid (ABTS) assay & anti-inflammatory activities by human blood cell (HRBC) membrane stabilization method & Inhibition of albumin denaturation method. The results obtained showed that the compound isolated from ethyl acetate fractions of C sativus flowers can be considered as good sources of antioxidants, anti-inflammatory & can be incorporated into the drug formulations.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.