Gmelina arborea (Kolkata) : vertus médicinales en extraction alcoolique

Gmelina arborea (Kolkata, Tèk blan, Teck blanc, White teak) — famille Verbénacées.

Synonymes scientifiques : Gmelina arborea var. glaucescens. Clarke, Premna arborea-Farw.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 7 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 52 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Écorce. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Nayak BS (2015)

     Extrait The plant Gmelina arborea has been traditionally used in India for several medicinal purposes like anthelmintic, diuretic, anti-inflammatory, antibacterial & antidiabetic. The antidiabetic activity of above extracts was evaluated in alloxan induced diabetic model of Wistar rats.

   • Selon Pattanayak P (2011)

     Extrait In the present investigation we have screened the Benzene, chloroform ethanolic, & aqueous extracts of the heart wood bark of the plant Gmelina arborea (family Verbenaceae) for antidiabetic activity in Streptozotocin (STZ) induced Diabetic rats and emphasized the mechanism of its antidiabetic property. The observed significant antidiabetic activity of the ethanolic extract could be attributed to the increased blood GSH levels reinforcing the role of GSH as free radical scavenger & in the repair of free radical caused biological damage.

   • Selon Kulkarni YA (2013)

     Extrait To study the effects of aqueous extract of Gmelina arborea bark on normoglycemic levels & streptozotocin (STZ) induced diabetes in rats. The diabetic animals were divided into four groups containing six in each: Group I diabetic control, Group II & III treated with the aqueous extract respectively at a dose of 250 & 500 mg/kg body weight once daily & Group IV treated with Glibenclamide at a dose of 0.6 mg/kg body weight once daily.

   • Selon Opara MN (s.d.)

     Extrait This study reveals the anti-diabetic properties of aqueous extracts & its ability to enhance renal function.

   • Selon Kayode O (2017)

     Extrait The animals were randomly grouped into four & assigned to four treatments of 0 (T1), 150 (T2), 300 (T3), & 450 mL/L (T4) of aqueous extracts of Gmelina arborea, prepared from freshly harvested GA leaves & administered through drinking water. This study reveals the anti-diabetic properties of aqueous extracts of GA leaves & its ability to enhance renal function.

2. 2

   Cancer : traitement adjuvant du carcinome oesophageal, colorectal, et gastrique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Auteur (2012)

     Extrait In the present study, the cytotoxicity of ethanolic leaf extracts of Gmelina arborea was tested against Colon cancer (COLO 201), Gastric cancer (HT- 29) & Human esophageal cancer (TE-2) cell lines using the thiazolyl blue test (MTT) assay. Cancer is one of the most common devastating disease affecting millions of people per Year.

   • Selon LUKMAN M (2014)

     Extrait Gmelina arborea Roxb, Guazuma ulmifolia Lamk & Curculigo orchioides Gaerth, the three plants frequently used in South Sulawesi for the treatment of cancerous diseases, have been selected to examine their action in cervical epithelial carcinoma. Dose-dependent studies revealed IC50 of 113.61±0.12 µg/mL, 174.90±1.22 µg/mL & 126.05±2.43 µg/mL for e-GA, e-GU & e-CO on HeLa cell cancer, respectively & correlated with treatment of cancer.

   • Selon Rohit S (s.d.)

     Extrait Aqueous Extract of Gmelina arborea Roxb (AEGA) was tested at the various concentrations 5, 10, 15 & 20 mg in MTT assay, Cell Viability assays & clonogenic assay. We tested the cytotoxic potential of Gmelina arborea Roxb in HL-60 cells.

   • Selon Auteur (2017)

     Extrait Gmelina arborea Roxb commonly known as ‘Gambhari’ tree, the various parts of the plants are widely used in diarrhoea, anti-pyretic, thirst, anemia, leprosy, ulcers, consumption, strangury & vaginal discharges. Overall, AEGA has shown a substantial & significant anti-cancer activity in all the models.

3. 3

   État inflammatoire : arthrose, arthrite , rhumatisme

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Nayak BS (2017)

     Extrait The anti-inflammatory activity of phytoconstituent was evaluated by Carrageenan-induced rat paw edema test method using Wistar rats as animal model. arborea & to explore the anti-inflammatory activity of isolated compound.

   • Selon Nayak BS (2015)

     Extrait The plant Gmelina arborea has been traditionally used in India for several medicinal purposes like anthelmintic, diuretic, anti-inflammatory, antibacterial & antidiabetic. arborea possess anthelmintic & antidiabetic activities,.

   • Selon Opara MN (s.d.)

     Extrait This study reveals the anti-diabetic properties of aqueous extracts & its ability to enhance renal function.

   • Selon Kayode O (2017)

     Extrait The animals were randomly grouped into four & assigned to four treatments of 0 (T1), 150 (T2), 300 (T3), & 450 mL/L (T4) of aqueous extracts of Gmelina arborea, prepared from freshly harvested GA leaves & administered through drinking water. This study reveals the anti-diabetic properties of aqueous extracts of GA leaves & its ability to enhance renal function.

   • Selon Rohit S (s.d.)

     Extrait Aqueous Extract of Gmelina arborea Roxb (AEGA) was tested at the various concentrations 5, 10, 15 & 20 mg in MTT assay, Cell Viability assays & clonogenic assay. We tested the cytotoxic potential of Gmelina arborea Roxb in HL-60 cells.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.